EXOSC9, exosome component 9

EXOSC9, exosome component 9

• This gene encodes a component of the human exosome, a exoribonuclease complex which processes and degrades RNA in the nucleus and cytoplasm. This component may play a role in mRNA degradation and the polymyositis/scleroderma autoantigen complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

• Gene Synonyms (exosome complex component RRP45, P75 polymyositis-scleroderma overlap syndrome associated autoantigen, PMSCL autoantigen, 75kD, autoantigen PM/Scl 1, exosome complex exonuclease RRP45, polymyositis/scleroderma autoantigen 1, 75kDa, PCH1D, PM/Scl-75, PMSCL1, RRP45, Rrp45p, p5, p6,)
• NCBI Gene ID: 5393
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q06265
  UNIPROT ID#>>B4DXG8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

exosome component 9 interacts with:

• 2-oxoglutarate and iron dependent oxygenase domain containing 1
  5'-3' exoribonuclease 2
  activation induced cytidine deaminase
  arginine and serine rich coiled-coil 1
  ariadne RBR E3 ubiquitin protein ligase 2
  ATPase H+ transporting V1 subunit G1
  bromodomain containing 7
  C1D nuclear receptor corepressor
  centrosomal AT-AC splicing factor
  charged multivesicular body protein 4B
  COP9 signalosome subunit 5
  cullin 3
  cullin associated and neddylation dissociated 1
  DAB2 interacting protein
  DExD-box helicase 39A
  DExD-box helicase 39B
  DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
  DIS3 like exosome 3'-5' exoribonuclease
  DNA primase subunit 2
  dynactin subunit 2
  elongation factor Tu GTP binding domain containing 2
  eukaryotic translation initiation factor 3 subunit D
  exosome component 1
  exosome component 1
  exosome component 10
  exosome component 2
  exosome component 3
  exosome component 4
  exosome component 5
  exosome component 6
  exosome component 7
  exosome component 8
  exosome component 9
  family with sequence similarity 111 member B
  F-box and WD repeat domain containing 8
  H3 clustered histone 1
  HBS1 like translational GTPase
  leucine rich repeat containing 47
  membrane palmitoylated protein 6
  mitogen-activated protein kinase kinase kinase 21
  M-phase phosphoprotein 6
  Mtr4 exosome RNA helicase
  NOP56 ribonucleoprotein
  nuclear distribution C, dynein complex regulator
  obscurin like cytoskeletal adaptor 1
  pelota mRNA surveillance and ribosome rescue factor
  PIH1 domain containing 1
  proteasome 20S subunit alpha 2
  proteasome 20S subunit alpha 5
  proteasome 20S subunit alpha 6
  proteasome 20S subunit alpha 7
  proteasome 26S subunit, non-ATPase 12
  pyrin and HIN domain family member 1
  RecQ like helicase 4
  ribosomal protein L36a
  RNA binding motif protein 7
  RTF1 homolog, Paf1/RNA polymerase II complex component
  slit guidance ligand 2
  small nuclear ribonucleoprotein U1 subunit 70
  small ubiquitin like modifier 2
  solute carrier family 35 member E1
  stromal antigen 1
  stromal antigen 2
  thyroid hormone receptor interactor 12
  transketolase
  tripartite motif containing 28
  ubiquitin conjugating enzyme E2 I
  ubiquitin specific peptidase 37
  zinc finger CCHC-type containing 9
  zinc finger DHHC-type palmitoyltransferase 17
  zinc finger protein 106
  zinc finger protein 830

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.