PRMT7, protein arginine methyltransferase 7

PRMT7, protein arginine methyltransferase 7

• This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients. [provided by RefSeq, May 2017]

• Gene Synonyms (protein arginine N-methyltransferase 7, [Myelin basic protein]-arginine N-methyltransferase PRMT7, histone-arginine N-methyltransferase PRMT7, SBIDDS,)
• NCBI Gene ID: 54496
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NVM4
  UNIPROT ID#>>A0A024R726
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein arginine methyltransferase 7 interacts with:

• CCCTC-binding factor like
  H3.5 histone
  inhibin subunit beta E
  IQ motif containing N
  NFKB inhibitor delta
  protein arginine methyltransferase 7
  TAFA chemokine like family member 3
  THAP domain containing 8
  zinc finger protein 438

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.