PPP2R5E, protein phosphatase 2 regulatory subunit B'epsilon

PPP2R5E, protein phosphatase 2 regulatory subunit B'epsilon

• The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

• Gene Synonyms (serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform, PP2A, B subunit, B' epsilon, PP2A, B subunit, B56 epsilon, PP2A, B subunit, PR61 epsilon, PP2A, B subunit, R5 epsilon, epsilon isoform of regulatory subunit B56, protein phosphatase 2A, protein phosphatase 2 regulatory subunit B', epsilon, protein phosphatase 2, regulatory subunit B (B56), epsilon isoform, serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, epsilon, B56E, B56epsilon,)
• NCBI Gene ID: 5529
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q16537
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 2 regulatory subunit B'epsilon interacts with:

• apoptosis inhibitor 5
  basic helix-loop-helix family member b9
  basic helix-loop-helix family member e41
  checkpoint kinase 2
  chromobox 5
  chromosome 19 open reading frame 57
  clock circadian regulator
  complement C1q like 4
  DDB1 and CUL4 associated factor 11
  deoxyribonuclease 2 beta
  DNA cross-link repair 1C
  family with sequence similarity 43 member A
  F-box and WD repeat domain containing 11
  gap junction protein beta 7
  general transcription factor II E, polypeptide 2 (beta subunit)
  kinase suppressor of ras 1
  Kruppel like factor 15
  limb development membrane protein 1 like
  Nanog homeobox
  NHS-like 1
  nucleotide binding oligomerization domain containing 2
  proline rich 14
  protein phosphatase 2 regulatory subunit B'epsilon
  protein phosphatase 2, regulatory subunit A, alpha
  proton activated chloride channel 1
  RAR related orphan receptor C
  RecQ like helicase 4
  ribosomal protein S27
  ring finger protein 4
  SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
  shugoshin 1
  shugoshin 2A
  SUMO1 activating enzyme subunit 1
  suppressor of glucose, autophagy associated 1
  TERF2 interacting protein
  TPD52 like 2
  tripartite motif containing 25
  tRNA methyltransferase 10A
  vesicle transport through interaction with t-SNAREs 1B
  V-set and immunoglobulin domain containing 1
  Wnt family member 3A
  zinc finger DHHC-type palmitoyltransferase 17
  zinc finger protein 517
  zinc finger protein 785
  zinc finger protein like 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.