MAPK13, mitogen-activated protein kinase 13

MAPK13, mitogen-activated protein kinase 13

• This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]

• Gene Synonyms (mitogen-activated protein kinase 13, MAP kinase 13, MAP kinase p38 delta, mitogen-activated protein kinase p38 delta, stress-activated protein kinase 4, MAPK 13, MAPK-13, PRKM13, SAPK4, p38delta,)
• NCBI Gene ID: 5603
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O15264
  UNIPROT ID#>>A0A024RD04
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitogen-activated protein kinase 13 interacts with:

• A-kinase interacting protein 1
  ankyrin repeat and LEM domain containing 2
  eukaryotic elongation factor 2 kinase
  HtrA serine peptidase 2
  MAPK activated protein kinase 3
  MAPK activated protein kinase 5
  mitogen-activated protein kinase 12
  mitogen-activated protein kinase 8 interacting protein 2
  mitogen-activated protein kinase kinase 6
  POTE ankyrin domain family member F
  sequestosome 1
  valosin containing protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.