PRPSAP2, phosphoribosyl pyrophosphate synthetase associated protein 2

PRPSAP2, phosphoribosyl pyrophosphate synthetase associated protein 2

• This gene encodes a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

• Gene Synonyms (phosphoribosyl pyrophosphate synthase-associated protein 2, 41 kDa phosphoribosypyrophosphate synthetase-associated protein, PRPP synthase-associated protein 2, PAP41,)
• NCBI Gene ID: 5636
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024QYY3
  UNIPROT ID#>>O60256
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphoribosyl pyrophosphate synthetase associated protein 2 interacts with:

• COP9 signalosome subunit 5
  dedicator of cytokinesis 7
  defective in cullin neddylation 1 domain containing 1
  elongation factor Tu GTP binding domain containing 2
  elongator acetyltransferase complex subunit 2
  endonuclease V
  influenza virus NS1A binding protein
  IQ motif containing GTPase activating protein 1
  leucine rich repeat containing 47
  leucine zipper like transcription regulator 1
  metadherin
  microtubule associated serine/threonine kinase 3
  mitochondrial translational release factor 1 like
  NSF attachment protein gamma
  nuclear receptor binding SET domain protein 2
  phosphoribosyl pyrophosphate synthetase 1 like 1
  phosphoribosyl pyrophosphate synthetase associated protein 2
  pleckstrin homology domain containing A2
  pleckstrin homology domain containing A4
  polypeptide N-acetylgalactosaminyltransferase 16
  proteasome 26S subunit, non-ATPase 10
  RecQ like helicase 4
  small nuclear ribonucleoprotein polypeptide B2
  snail family transcriptional repressor 1
  testis expressed 11
  TNFAIP3 interacting protein 2
  tripartite motif containing 28
  tumor protein, translationally-controlled 1
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  ubiquitin specific peptidase 15
  UBX domain protein 1
  vesicle transport through interaction with t-SNAREs 1B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.