SBF1, SET binding factor 1

SBF1, SET binding factor 1

• This gene encodes a member of the protein-tyrosine phosphatase family. However, the encoded protein does not appear to be a catalytically active phosphatase because it lacks several amino acids in the catalytic pocket. This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation. Mutations in this gene have been associated with Charcot-Marie-Tooth disease 4B3. Pseudogenes of this gene have been defined on chromosomes 1 and 8. [provided by RefSeq, Dec 2014]

• Gene Synonyms (myotubularin-related protein 5, DENN/MADD domain containing 7A, inactive phosphatidylinositol 3-phosphatase 5, CMT4B3, DENND7A, MTMR5,)
• NCBI Gene ID: 6305
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95248
  UNIPROT ID#>>A0A024R4Z9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SET binding factor 1 interacts with:

• apoptosis associated tyrosine kinase
  apoptotic chromatin condensation inducer 1
  CTTNBP2 N-terminal like
  egl-9 family hypoxia inducible factor 3
  F-box and WD repeat domain containing 11
  glucose-fructose oxidoreductase domain containing 1
  HEN methyltransferase 1
  hepatitis A virus cellular receptor 2
  INO80 complex subunit B
  intraflagellar transport 27
  intraflagellar transport 52
  leucine rich repeat containing 4C
  leucine zipper tumor suppressor 2
  MANSC domain containing 1
  mitochondrial ribosomal protein S16
  myotubularin related protein 1
  myotubularin related protein 2
  myotubularin related protein 2
  prostaglandin E synthase 3 like
  RAB35, member RAS oncogene family
  RAB6B, member RAS oncogene family
  regulator of hemoglobinization and erythroid cell expansion
  RNA polymerase II associated protein 3
  selectin E
  SET binding factor 1
  SET binding factor 2
  sirtuin 3
  sirtuin 7
  SPT16 homolog, facilitates chromatin remodeling subunit
  src kinase associated phosphoprotein 1
  stress induced phosphoprotein 1
  structure specific recognition protein 1
  suppressor of variegation 3-9 homolog 1
  TLE family member 1, transcriptional corepressor
  TNF superfamily member 11
  transforming growth factor beta receptor 2
  ubiquinol-cytochrome c reductase complex assembly factor 1
  ubiquinol-cytochrome c reductase complex assembly factor 2
  WD repeat domain 55
  zinc finger HIT-type containing 1
  zinc ribbon domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.