SNRPE, small nuclear ribonucleoprotein polypeptide E

SNRPE, small nuclear ribonucleoprotein polypeptide E

• The protein encoded by this gene is a core component of U small nuclear ribonucleoproteins, which are key components of the pre-mRNA processing spliceosome. The encoded protein plays a role in the 3' end processing of histone transcripts. This protein is one of the targets in the autoimmune disease systemic lupus erythematosus, and mutations in this gene have been associated with hypotrichosis. Several pseudogenes of this gene have been identified. [provided by RefSeq, Jun 2016]

• Gene Synonyms (small nuclear ribonucleoprotein E, sm protein E, HYPT11, SME, Sm-E, snRNP-E,)
• NCBI Gene ID: 6635
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P62304
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

small nuclear ribonucleoprotein polypeptide E interacts with:

• 2'-5'-oligoadenylate synthetase like
  AAR2 splicing factor
  A-kinase anchoring protein 7
  aquarius intron-binding spliceosomal factor
  arginine and serine rich coiled-coil 1
  ariadne RBR E3 ubiquitin protein ligase 2
  calcium homeostasis endoplasmic reticulum protein
  cap methyltransferase 2
  CD2 cytoplasmic tail binding protein 2
  cell division cycle 37, HSP90 cochaperone
  cell division cycle 40
  centrosomal AT-AC splicing factor
  coiled-coil domain containing 12
  COP9 signalosome subunit 5
  crooked neck pre-mRNA splicing factor 1
  cullin 1
  cullin 2
  cullin 3
  cullin 4A
  cullin 4B
  cullin 5
  cullin 7
  cullin associated and neddylation dissociated 1
  CWF19 like cell cycle control factor 1
  CWF19 like cell cycle control factor 2
  DEAD-box helicase 20
  DEAD-box helicase 23
  DEAD-box helicase 42
  DEAD-box helicase 46
  DEAH-box helicase 35
  decapping enzyme, scavenger
  defective in cullin neddylation 1 domain containing 1
  DNA topoisomerase II beta
  E2F associated phosphoprotein
  elongation factor Tu GTP binding domain containing 2
  ess-2 splicing factor homolog
  eukaryotic translation initiation factor 3, subunit I
  GC-rich sequence DNA-binding factor 2
  gem nuclear organelle associated protein 2
  gem nuclear organelle associated protein 4
  gem nuclear organelle associated protein 5
  gem nuclear organelle associated protein 6
  gem nuclear organelle associated protein 7
  gem nuclear organelle associated protein 8
  geranylgeranyl diphosphate synthase 1
  G-patch domain containing 1
  G-patch domain containing 11
  H2A clustered histone 4
  H4 clustered histone 1
  HEXIM P-TEFb complex subunit 1
  HIV-1 Tat specific factor 1
  integrin alpha FG-GAP repeat containing 1
  ISY1 splicing factor homolog
  La ribonucleoprotein 7, transcriptional regulator
  LSM1 homolog, mRNA degradation associated
  LSM11, U7 small nuclear RNA associated
  LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
  LUC7 like 2, pre-mRNA splicing factor
  methylphosphate capping enzyme
  methyltransferase like 14
  microtubule associated protein RP/EB family member 1
  nuclear receptor subfamily 2 group C member 2
  Obg like ATPase 1
  obscurin like cytoskeletal adaptor 1
  PAX3 and PAX7 binding protein 1
  peptidylprolyl isomerase E
  pre-mRNA processing factor 3
  pre-mRNA processing factor 31
  pre-mRNA processing factor 4
  pre-mRNA processing factor 6
  pre-mRNA processing factor 8
  pre-mRNA processing factor 8
  PRKR interacting protein 1
  programmed cell death 7
  protein arginine methyltransferase 5
  RecQ like helicase 4
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 181
  ring-box 1
  RIO kinase 1
  RNA binding motif protein 22
  RNA binding motif protein 42
  RNA binding motif protein 5
  RNA binding region (RNP1, RRM) containing 3
  serine and arginine repetitive matrix 1
  serine/threonine kinase receptor associated protein
  small nuclear ribonucleoprotein polypeptide E
  small nuclear ribonucleoprotein polypeptide F
  small nuclear ribonucleoprotein polypeptide G
  small nuclear ribonucleoprotein polypeptide N
  small nuclear ribonucleoprotein U11/U12 subunit 35
  small nuclear ribonucleoprotein U11/U12 subunit 48
  small nuclear ribonucleoprotein U4/U6.U5 subunit 27
  small nuclear ribonucleoprotein U5 subunit 200
  small nuclear ribonucleoprotein U5 subunit 40
  SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
  snurportin 1
  SNW domain containing 1
  SNW domain containing 1
  solute carrier family 15 member 3
  solute carrier family 4 member 1 adaptor protein
  spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
  spliceosome associated factor 3, U4/U6 recycling protein
  splicing factor 3a subunit 1
  splicing factor 3a subunit 2
  splicing factor 3a subunit 3
  splicing factor 3a, subunit 1
  splicing factor 3b subunit 1
  splicing factor 3b subunit 2
  splicing factor 3b subunit 3
  splicing factor 3b subunit 4
  splicing factor 3b subunit 5
  splicing factor 3b subunit 6
  SYF2 pre-mRNA splicing factor
  target of EGR1, exonuclease
  TATA-box binding protein associated factor 15
  TBC1 domain family member 9
  terminal uridylyl transferase 1, U6 snRNA-specific
  trimethylguanosine synthase 1
  tuftelin interacting protein 11
  tumor necrosis factor
  tumor suppressing subtransferable candidate 4
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  U2 snRNP associated SURP domain containing
  ubiquitin conjugating enzyme E2 M
  ubiquitin like 4A
  unc-93 homolog B1, TLR signaling regulator
  unk zinc finger
  vir like m6A methyltransferase associated
  VRK serine/threonine kinase 1
  WD repeat domain 77
  WD repeat domain 83
  XPA binding protein 2
  zinc finger CCCH-type and G-patch domain containing
  zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
  zinc finger matrin-type 5
  zinc finger MYM-type containing 4
  zinc finger protein 830

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.