SSTR5, somatostatin receptor 5

SSTR5, somatostatin receptor 5

• Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010]

• Gene Synonyms (somatostatin receptor type 5, somatostatin receptor subtype 5, SS-5-R,)
• NCBI Gene ID: 6755
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P35346
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

somatostatin receptor 5 interacts with:

• adenylate cyclase 10
  amine oxidase copper containing 3
  golgi associated PDZ and coiled-coil motif containing
  somatostatin receptor 5

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