CAVIN2, caveolae associated protein 2

CAVIN2, caveolae associated protein 2

• This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]

• Gene Synonyms (caveolae-associated protein 2, phosphatidylserine-binding protein, serum deprivation response, serum deprivation-response protein, PS-p68, SDPR, SDR, cavin-2,)
• NCBI Gene ID: 8436
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95810
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

caveolae associated protein 2 interacts with:

• APOBEC1 complementation factor
  caveolae associated protein 2
  FANCD2 and FANCI associated nuclease 1
  mediator of DNA damage checkpoint 1
  microspherule protein 1
  nudix hydrolase 18
  pleckstrin homology and FYVE domain containing 1
  pleckstrin homology and FYVE domain containing 2
  SET nuclear oncogene
  trafficking protein particle complex 6A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.