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SORBS2, sorbin and SH3 domain containing 2

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SORBS2, sorbin and SH3 domain containing 2

  • Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

  • Gene Synonyms (sorbin and SH3 domain-containing protein 2, Arg binding protein 2, Arg/Abl-interacting protein 2, arg-binding protein 2, ARGBP2, PRO0618,)
  • NCBI Gene ID: 8470
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>B7Z997
    UNIPROT ID#>>O94875
    UNIPROT ID#>>B7Z3D7
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sorbin and SH3 domain containing 2 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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