CD40LG, CD40 ligand

CD40LG, CD40 ligand

• The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CD40 ligand, CD40 antigen ligand, CD40-L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein, tumor necrosis factor (ligand) superfamily member 5, CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L,)
• NCBI Gene ID: 959
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P29965
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CD40 ligand interacts with:

• CD40 ligand
  crystallin alpha B
  haptoglobin-related protein
  ring finger protein 128
  TNF receptor associated factor 1
  TNF receptor associated factor 2
  tumor protein p53

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.