CSF2RB, colony stimulating factor 2 receptor subunit beta

CSF2RB, colony stimulating factor 2 receptor subunit beta

• The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]

• Gene Synonyms (cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta subunit, GM-CSF/IL-3/IL-5 receptor common beta-chain, beta common cytokine receptor, beta-GM-CSF receptor, colony stimulating factor 2 receptor beta common subunit, colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage), colony-stimulating factor-2 receptor, beta, low-affinity, interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity), CD131, CDw131, IL3RB, IL5RB, SMDP5, betaGMR,)
• NCBI Gene ID: 1439
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P32927
  UNIPROT ID#>>Q6NSJ8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

colony stimulating factor 2 receptor subunit beta interacts with:

• colony stimulating factor 2 receptor subunit beta
  erythropoietin receptor
  FES proto-oncogene, tyrosine kinase
  FYN proto-oncogene, Src family tyrosine kinase
  HCK proto-oncogene, Src family tyrosine kinase
  inhibitor of nuclear factor kappa B kinase subunit beta
  interleukin 3
  interleukin 3 receptor subunit alpha
  interleukin 5 receptor subunit alpha
  Janus kinase 1
  Janus kinase 2
  kinase insert domain receptor
  KIT proto-oncogene, receptor tyrosine kinase
  LCK proto-oncogene, Src family tyrosine kinase
  LYN proto-oncogene, Src family tyrosine kinase
  mitotic arrest deficient 2 like 1
  protein kinase C beta
  protein tyrosine phosphatase non-receptor type 11
  protein tyrosine phosphatase non-receptor type 6
  receptor for activated C kinase 1
  SHC adaptor protein 1
  signal transducer and activator of transcription 1
  signal transducer and activator of transcription 3
  spleen associated tyrosine kinase
  suppressor of cytokine signaling 1
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.