ENDOG, endonuclease G

ENDOG, endonuclease G

• The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008]

• Gene Synonyms (endonuclease G, mitochondrial, endo G, mitochondrial endonuclease G,)
• NCBI Gene ID: 2021
• Species: Homo sapiens (Human)
• UNIPROT ID#>>E5KNL5
  UNIPROT ID#>>Q14249
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

endonuclease G interacts with:

• apoptosis inducing factor mitochondria associated 1
  aurora kinase B
  BAG cochaperone 4
  carboxypeptidase A4
  cytochrome c oxidase assembly factor COX14
  DnaJ heat shock protein family (Hsp40) member A1
  DnaJ heat shock protein family (Hsp40) member A4
  Enah/Vasp-like
  EPH receptor A8
  flap structure-specific endonuclease 1
  G protein-coupled receptor kinase 6
  heat shock protein family A (Hsp70) member 4
  heat shock protein family A (Hsp70) member 8
  intelectin 1
  intelectin 2
  nuclear transcription factor Y subunit gamma
  patched 1
  plasminogen receptor with a C-terminal lysine
  polycomb group ring finger 2
  protein kinase cAMP-activated catalytic subunit gamma
  sideroflexin 1
  STIP1 homology and U-box containing protein 1
  synthesis of cytochrome C oxidase 1
  tropomyosin 1
  zinc ribbon domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.