SCO1, synthesis of cytochrome C oxidase 1

SCO1, synthesis of cytochrome C oxidase 1

• Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (protein SCO1 homolog, mitochondrial, SCO cytochrome c oxidase assembly protein 1, SCO cytochrome oxidase deficient homolog 1, SCO1, cytochrome c oxidase assembly protein, SCOD1,)
• NCBI Gene ID: 6341
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75880
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

synthesis of cytochrome C oxidase 1 interacts with:

• acyl-CoA thioesterase 1
  acyl-CoA thioesterase 2
  AFG3 like matrix AAA peptidase subunit 2
  A-kinase anchoring protein 1
  A-kinase anchoring protein 12
  apolipoprotein O like
  ATPase family AAA domain containing 3B
  baculoviral IAP repeat containing 6
  caseinolytic mitochondrial matrix peptidase chaperone subunit B
  caseinolytic mitochondrial matrix peptidase chaperone subunit X
  caseinolytic mitochondrial matrix peptidase proteolytic subunit
  CDGSH iron sulfur domain 3
  cell death inducing DFFA like effector b
  cell division cycle associated 3
  chromosome 1 open reading frame 198
  citron rho-interacting serine/threonine kinase
  coiled-coil domain containing 51
  coiled-coil domain containing 58
  coiled-coil-helix-coiled-coil-helix domain containing 3
  coiled-coil-helix-coiled-coil-helix domain containing 4
  coiled-coil-helix-coiled-coil-helix domain containing 6
  crystallin beta-gamma domain containing 3
  C-X9-C motif containing 2
  C-X9-C motif containing 4
  cytochrome c oxidase assembly factor 6
  cytochrome c oxidase assembly factor 7 (putative)
  cytochrome c oxidase assembly factor COX14
  cytochrome c oxidase assembly factor COX16
  cytochrome c oxidase assembly factor COX19
  cytochrome c oxidase copper chaperone COX17
  cytochrome c oxidase subunit 5A
  DnaJ heat shock protein family (Hsp40) member C11
  elongation factor Tu GTP binding domain containing 2
  family with sequence similarity 136 member A
  HCLS1 associated protein X-1
  hypoxia inducible factor 1 subunit alpha inhibitor
  inner membrane mitochondrial protein
  isoleucyl-tRNA synthetase 2, mitochondrial
  KIAA1191
  lactamase beta
  leucine rich pentatricopeptide repeat containing
  MAPK associated protein 1
  mediator complex subunit 23
  mediator complex subunit 4
  metaxin 2
  metaxin 3
  mitochondrial antiviral signaling protein
  mitochondrial calcium uptake 2
  mitochondrial ribosomal protein S14
  mitochondrial ribosomal protein S22
  mitochondrial ribosomal protein S23
  mitochondrial ribosomal protein S31
  mitochondrial ribosomal protein S36
  myotubularin related protein 12
  NADH:ubiquinone oxidoreductase core subunit S7
  nucleoporin 93
  OCIA domain containing 1
  outer mitochondrial membrane lipid metabolism regulator OPA3
  pentatricopeptide repeat domain 3
  plasminogen receptor with a C-terminal lysine
  pyrroline-5-carboxylate reductase 2
  receptor interacting serine/threonine kinase 4
  SAMM50 sorting and assembly machinery component
  SEC16 homolog A, endoplasmic reticulum export factor
  sequestosome 1
  sideroflexin 1
  small integral membrane protein 12
  solute carrier family 25 member 12
  solute carrier family 25 member 13
  synapse associated protein 1
  synaptosome associated protein 29
  synaptotagmin binding cytoplasmic RNA interacting protein
  synthesis of cytochrome C oxidase 1
  synthesis of cytochrome C oxidase 2
  tetratricopeptide repeat domain 19
  titin
  TP53 regulated inhibitor of apoptosis 1
  translocase of inner mitochondrial membrane 10
  translocase of inner mitochondrial membrane 13
  translocase of inner mitochondrial membrane 8 homolog B
  translocase of inner mitochondrial membrane 9
  translocase of inner mitochondrial membrane domain containing 1
  translocase of outer mitochondrial membrane 20
  translocase of outer mitochondrial membrane 22
  translocase of outer mitochondrial membrane 70
  transmembrane protein 126B
  ubiquinol-cytochrome c reductase core protein 1
  ubiquinol-cytochrome c reductase core protein 2
  ubiquitin protein ligase E3 component n-recognin 4
  WD repeat domain 19
  YME1 like 1 ATPase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.