FLT4, fms related receptor tyrosine kinase 4

FLT4, fms related receptor tyrosine kinase 4

• This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CHTD7, FLT-4, FLT41, LMPH1A, LMPHM1, PCL, VEGFR-3, VEGFR3, vascular endothelial growth factor receptor 3, Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4, VEGF receptor-3, fms related tyrosine kinase 4, fms-like tyrosine kinase 4, primary congenital lymphedema, tyrosine-protein kinase receptor FLT4,)
• NCBI Gene ID: 2324
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P35916
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

fms related receptor tyrosine kinase 4 interacts with:

• activating transcription factor 7 interacting protein
  dual specificity phosphatase 19
  epsin 1
  fms related receptor tyrosine kinase 4
  galectin 3
  galectin 8
  growth factor receptor bound protein 2
  heat shock protein 90 alpha family class A member 1
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  integrin subunit alpha 5
  integrin subunit beta 1
  kinase insert domain receptor
  leucine rich repeat kinase 1
  lipase H
  MAS1 proto-oncogene, G protein-coupled receptor
  NEDD4 E3 ubiquitin protein ligase
  neuropeptide Y receptor Y2
  plasmalemma vesicle associated protein
  prostaglandin E receptor 3
  protein tyrosine kinase 2
  protein tyrosine phosphatase non-receptor type 11
  protocadherin gamma subfamily B, 1
  SHC adaptor protein 1
  SHC adaptor protein 3
  transmembrane protein 52B
  tumor necrosis factor
  vascular endothelial growth factor C
  vascular endothelial growth factor D
  V-set and immunoglobulin domain containing 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.