FUT1, fucosyltransferase 1 (H blood group)

FUT1, fucosyltransferase 1 (H blood group)

• This gene encodes a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the synthesis of soluble A and B antigens. This is one of two genes encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group. [provided by RefSeq, Aug 2016]

• Gene Synonyms (H, HH, HSC, galactoside alpha-(1,2)-fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, H glycosyltransferase, H glycosytransferase, alpha(1,2) fucosyltransferase 1, alpha(1,2)FT 1, blood group H alpha 2-fucosyltransferase, galactoside 2-alpha-L-fucosyltransferase, nonfunctional fucosyltransferase 1, truncated FUT1, truncated alpha(1,2)fucosyltransferase, truncated fucosyltransferase 1, type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1, type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1,)
• NCBI Gene ID: 2523
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P19526
  UNIPROT ID#>>Q6IZA2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

fucosyltransferase 1 (H blood group) interacts with:

• chondroitin sulfate N-acetylgalactosaminyltransferase 2
  galactosidase beta 1 like 2
  glycosyltransferase 8 domain containing 2
  golgi integral membrane protein 4
  HtrA serine peptidase 1
  mitochondrially encoded NADH dehydrogenase 5
  NADH:ubiquinone oxidoreductase subunit A7
  NADH:ubiquinone oxidoreductase subunit B5
  NADH:ubiquinone oxidoreductase subunit B6
  NADH:ubiquinone oxidoreductase subunit B8
  NADH:ubiquinone oxidoreductase subunit B9
  NADH:ubiquinone oxidoreductase subunit S4
  phosphatidylinositol glycan anchor biosynthesis class B
  solute carrier family 9 member A1
  UDP glycosyltransferase 8
  UDP glycosyltransferase family 3 member A2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.