GNAO1, G protein subunit alpha o1

GNAO1, G protein subunit alpha o1

• The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

• Gene Synonyms (guanine nucleotide-binding protein G(o) subunit alpha, GO2-q chimeric G-protein, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, guanine nucleotide-binding regulatory protein 2, EIEE17, G-ALPHA-o, GNAO, HLA-DQB1, NEDIM,)
• NCBI Gene ID: 2775
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P09471
  UNIPROT ID#>>Q6AWC5
  UNIPROT ID#>>Q8N6I9
  UNIPROT ID#>>B3KP89
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

G protein subunit alpha o1 interacts with:

• armadillo repeat containing 1
  BAG cochaperone 3
  dual specificity phosphatase 22
  dynactin subunit 2
  dynein axonemal assembly factor 2
  free fatty acid receptor 2
  G protein signaling modulator 2
  G protein subunit alpha o1
  G protein subunit gamma 3
  G protein-coupled receptor 35
  gap junction protein beta 7
  glutamate metabotropic receptor 6
  HAUS augmin-like complex, subunit 4
  HCLS1 associated protein X-1
  histamine receptor H4
  homeobox B5
  huntingtin
  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
  junctional sarcoplasmic reticulum protein 1
  kelch like family member 3
  kinesin associated protein 3
  mediator complex subunit 4
  neuroglobin
  neurotrophic receptor tyrosine kinase 1
  nuclear FMR1 interacting protein 1
  nucleobindin 1
  opioid receptor delta 1
  opioid receptor mu 1
  pericentriolar material 1
  phosphodiesterase 6G
  phosphodiesterase 6H
  protein tyrosine phosphatase receptor type U
  regulator of G protein signaling 1
  regulator of G protein signaling 10
  regulator of G protein signaling 14
  regulator of G protein signaling 16
  regulator of G protein signaling 19
  regulator of G protein signaling 20
  regulator of G protein signaling 4
  regulator of G protein signaling 5
  regulator of G protein signaling 7
  regulator of G protein signaling 9
  RIC8 guanine nucleotide exchange factor A
  sodium voltage-gated channel alpha subunit 8
  solute carrier family 30 member 4
  sphingosine-1-phosphate receptor 5
  thyroid stimulating hormone receptor
  transcription factor CP2
  tropomodulin 3
  vir like m6A methyltransferase associated
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.