GOT2, glutamic-oxaloacetic transaminase 2

GOT2, glutamic-oxaloacetic transaminase 2

• Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

• Gene Synonyms (aspartate aminotransferase, mitochondrial, FABP-1, FABPpm, aspartate aminotransferase 2, aspartate transaminase 2, fatty acid-binding protein, glutamate oxaloacetate transaminase 2, glutamic-oxaloacetic transaminase 2, mitochondrial, kynurenine aminotransferase 4, kynurenine aminotransferase IV, kynurenine--oxoglutarate transaminase 4, kynurenine--oxoglutarate transaminase IV, mAspAT, plasma membrane-associated fatty acid-binding protein, transaminase A, KAT4, KATIV, KYAT4, mitAAT,)
• NCBI Gene ID: 2806
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P00505
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glutamic-oxaloacetic transaminase 2 interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  apoptosis inducing factor mitochondria associated 1
  catenin beta interacting protein 1
  C-C motif chemokine ligand 21
  cullin 7
  cytochrome c oxidase copper chaperone COX17
  expressed sequence AI837181
  glucose-6-phosphate isomerase
  glycogenin 1
  heat shock protein family A (Hsp70) member 8
  histone deacetylase 5
  hydroxyacyl-CoA dehydrogenase
  kynurenine aminotransferase 3
  malate dehydrogenase 2
  methylphosphate capping enzyme
  methyltransferase like 14
  MYC proto-oncogene, bHLH transcription factor
  neurotrophic receptor tyrosine kinase 1
  N-methylpurine DNA glycosylase
  peroxiredoxin 5
  phosphoethanolamine/phosphocholine phosphatase 1
  prolyl endopeptidase like
  prostaglandin reductase 1
  proteasome 26S subunit, non-ATPase 4
  pyruvate carboxylase
  RAB11B, member RAS oncogene family
  TAR DNA binding protein
  thioredoxin
  thioredoxin domain containing 12
  THO complex 7
  TNFAIP3 interacting protein 2
  U2 small nuclear RNA auxiliary factor 2
  zinc finger DHHC-type palmitoyltransferase 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.