GP2, glycoprotein 2

GP2, glycoprotein 2

• This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

• Gene Synonyms (pancreatic secretory granule membrane major glycoprotein GP2, glycoprotein 2 (zymogen granule membrane), pancreatic zymogen granule membrane associated protein GP2, ZAP75,)
• NCBI Gene ID: 2813
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z1G2
  UNIPROT ID#>>Q68D34
  UNIPROT ID#>>P55259
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glycoprotein 2 interacts with:

• glycoprotein 2
  jagunal homolog 1
  SRY-box transcription factor 30
  testis specific serine kinase 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.