HIC1, HIC ZBTB transcriptional repressor 1

HIC1, HIC ZBTB transcriptional repressor 1

• This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2010]

• Gene Synonyms (hypermethylated in cancer 1 protein, hypermethylated in cancer 1, zinc finger and BTB domain-containing protein 29, ZBTB29, ZNF901, hic-1,)
• NCBI Gene ID: 3090
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14526
  UNIPROT ID#>>A0PJI1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

HIC ZBTB transcriptional repressor 1 interacts with:

• AT-rich interaction domain 1A
  BAF chromatin remodeling complex subunit BCL11B
  cereblon
  C-terminal binding protein 1
  cullin 4A
  embryonic ectoderm development
  HIC ZBTB transcriptional repressor 1
  HIC ZBTB transcriptional repressor 2
  high mobility group AT-hook 1
  histone deacetylase 4
  metastasis associated 1
  methyl-CpG binding domain protein 3
  PHD finger protein 1
  PHD finger protein 19
  protein inhibitor of activated STAT 1
  protein inhibitor of activated STAT 2
  protein inhibitor of activated STAT 3
  protein inhibitor of activated STAT 4
  RB binding protein 4, chromatin remodeling factor
  signal transducer and activator of transcription 3
  sirtuin 1
  Sp1 transcription factor
  SUMO specific peptidase 3
  SUZ12 polycomb repressive complex 2 subunit
  transcription factor 7 like 2
  tripartite motif containing 25
  ubiquitin conjugating enzyme E2 I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.