IL1R1, interleukin 1 receptor type 1

IL1R1, interleukin 1 receptor type 1

• This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013]

• Gene Synonyms (interleukin-1 receptor type 1, CD121 antigen-like family member A, IL-1R-1, IL-1RT-1, IL-1RT1, interleukin 1 receptor alpha, type I, interleukin-1 receptor alpha, interleukin-1 receptor type I, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80,)
• NCBI Gene ID: 3554
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B8ZZW4
  UNIPROT ID#>>P14778
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interleukin 1 receptor type 1 interacts with:

• ciliogenesis associated kinase 1
  homocysteine inducible ER protein with ubiquitin like domain 1
  interleukin 1 family member 10
  interleukin 1 receptor accessory protein
  interleukin 1 receptor antagonist
  interleukin 1 receptor associated kinase 1
  interleukin 1 receptor associated kinase 2
  interleukin 1 receptor associated kinase 4
  LYN proto-oncogene, Src family tyrosine kinase
  membrane associated ring-CH-type finger 8
  microfibril associated protein 3
  MYD88 innate immune signal transduction adaptor
  pellino E3 ubiquitin protein ligase 1
  phosphoinositide-3-kinase regulatory subunit 1
  single Ig and TIR domain containing
  SRC proto-oncogene, non-receptor tyrosine kinase
  target of myb1 membrane trafficking protein
  TNF receptor associated factor 6
  TNF receptor superfamily member 10b
  toll interacting protein
  toll like receptor adaptor molecule 2
  tubulin beta 8 class VIII
  YES proto-oncogene 1, Src family tyrosine kinase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.