ITPK1, inositol-tetrakisphosphate 1-kinase

ITPK1, inositol-tetrakisphosphate 1-kinase

• This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X. [provided by RefSeq, Jul 2016]

• Gene Synonyms (ITRPK1, inositol-tetrakisphosphate 1-kinase, inositol 1,3,4-trisphosphate 5/6-kinase, ins(1,3,4)P(3) 5/6-kinase,)
• NCBI Gene ID: 3705
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R6H3
  UNIPROT ID#>>Q13572
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

inositol-tetrakisphosphate 1-kinase interacts with:

• COP9 signalosome subunit 8
  crystallin zeta like 1
  dynein axonemal assembly factor 5
  inositol-tetrakisphosphate 1-kinase
  Jun proto-oncogene, AP-1 transcription factor subunit
  mitogen-activated protein kinase 1
  Mov10 RISC complex RNA helicase
  NFKB inhibitor alpha
  nuclear receptor subfamily 2 group C member 2
  pleckstrin homology domain containing A4
  sodium voltage-gated channel beta subunit 2
  TNF receptor associated factor 2
  tripartite motif containing 25
  tumor protein p53

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.