KCNN4, potassium calcium-activated channel subfamily N member 4

KCNN4, potassium calcium-activated channel subfamily N member 4

• The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008]

• Gene Synonyms (DHS2, IK, IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4, intermediate conductance calcium-activated potassium channel protein 4, SKCa 4, SKCa4, potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, putative Gardos channel, putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel, small conductance calcium-activated potassium channel 4,)
• NCBI Gene ID: 3783
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O15554
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium calcium-activated channel subfamily N member 4 interacts with:

• calmodulin-like 3
  cornichon family AMPA receptor auxiliary protein 3
  FXYD domain containing ion transport regulator 3
  G protein-coupled receptor 152
  peripheral myelin protein 22
  protein kinase AMP-activated non-catalytic subunit gamma 1
  RAB7A, member RAS oncogene family
  solute carrier family 30 member 2
  syntaxin 1B
  tumor susceptibility 101
  ubiquitin specific peptidase 8

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.