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ME2, malic enzyme 2

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ME2, malic enzyme 2

  • This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009]

  • Gene Synonyms (ODS1, NAD-dependent malic enzyme, mitochondrial, NAD-ME, malate dehydrogenase (oxaloacetate-decarboxylating), malic enzyme 2, NAD(+)-dependent, mitochondrial, pyruvic-malic carboxylase,)
  • NCBI Gene ID: 4200
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>P23368
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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