CNOT4, CCR4-NOT transcription complex subunit 4

CNOT4, CCR4-NOT transcription complex subunit 4

• The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]

• Gene Synonyms (CLONE243, NOT4, NOT4H, CCR4-NOT transcription complex subunit 4, CCR4-associated factor 4, E3 ubiquitin-protein ligase CNOT4, NOT4 (negative regulator of transcription 4, yeast) homolog, RING-type E3 ubiquitin transferase CNOT4, potential transcriptional repressor NOT4Hp,)
• NCBI Gene ID: 4850
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R781
  UNIPROT ID#>>A0A024R785
  UNIPROT ID#>>O95628
  UNIPROT ID#>>A0A024R776
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CCR4-NOT transcription complex subunit 4 interacts with:

• CCR4-NOT transcription complex subunit 1
  CCR4-NOT transcription complex subunit 4
  CCR4-NOT transcription complex subunit 6
  CCR4-NOT transcription complex subunit 8
  CCR4-NOT transcription complex subunit 9
  exportin 1
  interleukin 36 receptor antagonist
  lysine demethylase 5C
  RNA binding motif protein 15
  ubiquitin conjugating enzyme E2 B
  ubiquitin conjugating enzyme E2 D1
  ubiquitin conjugating enzyme E2 D2
  ubiquitin conjugating enzyme E2 D3
  ubiquitin conjugating enzyme E2 D4 (putative)
  ubiquitin conjugating enzyme E2 E1
  ubiquitin conjugating enzyme E2 E3
  ubiquitin conjugating enzyme E2 N
  ubiquitin conjugating enzyme E2 W

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.