Skip Navigation Links Home » Resources » Gene Detail

POU5F1, POU class 5 homeobox 1

Matching ORF Clones

Request a Custom Clone

Don't see what you need?

Request My Custom Clone »
  • Gene Overview
  • Interaction Network
  • Sequence Verification

POU5F1, POU class 5 homeobox 1

  • This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]

  • Gene Synonyms (POU domain, class 5, transcription factor 1, POU class 5 homeobox 1 transcript variant OCT4B1, POU class 5 homeobox 1 transcript variant OCT4B2, POU class 5 homeobox 1 transcript variant OCT4B3, POU class 5 homeobox 1 transcript variant OCT4B4, POU class 5 homeobox 1 transcript variant OCT4B5, POU class 5 homeobox 1 transcript variant OCT4B6, POU classV homeobox 1 variant 2, POU domain transcription factor OCT4, POU-type homeodomain-containing DNA-binding protein, octamer-binding protein 3, octamer-binding protein 4, octamer-binding transcription factor 3, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4,)
  • NCBI Gene ID: 5460
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>D2IYK3
    UNIPROT ID#>>M1S623
    UNIPROT ID#>>F2Z381
    UNIPROT ID#>>Q01860
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

POU class 5 homeobox 1 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

It appears that you have Javascript disabled. Our website requires Javascript to function correctly. For the best browsing experience, please enable Javascript.