SOX6, SRY-box transcription factor 6

SOX6, SRY-box transcription factor 6

• This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

• Gene Synonyms (HSSOX6, SOXD, transcription factor SOX-6, SRY (sex determining region Y)-box 6, SRY-box 6, SRY-box containing gene 6,)
• NCBI Gene ID: 55553
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P35712
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SRY-box transcription factor 6 interacts with:

• centromere protein K
  protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
  SRY-box transcription factor 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.