SPINT1, serine peptidase inhibitor, Kunitz type 1

SPINT1, serine peptidase inhibitor, Kunitz type 1

• The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Gene Synonyms (kunitz-type protease inhibitor 1, HAI-1, hepatocyte growth factor activator inhibitor type 1, serine protease inhibitor, Kunitz type 1, HAI, HAI1, MANSC2,)
• NCBI Gene ID: 6692
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43278
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serine peptidase inhibitor, Kunitz type 1 interacts with:

• ADAM metallopeptidase domain 33
  anterior gradient 3, protein disulphide isomerase family member
  C-type lectin domain containing 7A
  DDB1 and CUL4 associated factor 4
  FAM3 metabolism regulating signaling molecule C
  keratin associated protein 1-3
  neuroligin 3
  single-pass membrane protein with coiled-coil domains 4
  solute carrier family 38 member 7
  ST14 transmembrane serine protease matriptase
  terminal nucleotidyltransferase 5A
  tetraspanin 33
  transferrin
  transmembrane protein 109
  transmembrane protein 190
  transmembrane protein 97
  ubiquilin 2
  ubiquilin 4
  uroplakin 1B
  vesicle associated membrane protein 5
  zinc finger protein 250

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.