Skip Navigation Links Home » Resources » Gene Detail

TFE3, transcription factor binding to IGHM enhancer 3

Matching ORF Clones

Request a Custom Clone

Don't see what you need?

Request My Custom Clone »
  • Gene Overview
  • Interaction Network
  • Sequence Verification

TFE3, transcription factor binding to IGHM enhancer 3

  • This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

  • Gene Synonyms (transcription factor E3, class E basic helix-loop-helix protein 33, transcription factor E family, member A, transcription factor for IgH enhancer, transcription factor for immunoglobulin heavy-chain enhancer 3, RCCP2, RCCX1, TFEA, bHLHe33,)
  • NCBI Gene ID: 7030
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>B4DIA5
    UNIPROT ID#>>A0A024QZ23
    UNIPROT ID#>>P19532
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transcription factor binding to IGHM enhancer 3 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

It appears that you have Javascript disabled. Our website requires Javascript to function correctly. For the best browsing experience, please enable Javascript.