PLPP1, phospholipid phosphatase 1

PLPP1, phospholipid phosphatase 1

• The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in synthesis of glycerolipids and in phospholipase D-mediated signal transduction. This enzyme is an integral membrane glycoprotein that plays a role in the hydrolysis and uptake of lipids from extracellular space. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

• Gene Synonyms (phospholipid phosphatase 1, lipid phosphate phosphohydrolase 1a, phosphatidate phosphohydrolase type 2a, phosphatidic acid phosphatase 2a, phosphatidic acid phosphatase type 2A, phosphatidic acid phosphohydrolase type 2a, type-2 phosphatidic acid phosphatase alpha, LLP1a, LPP1, PAP-2a, PAP2, PPAP2A,)
• NCBI Gene ID: 8611
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14494
  UNIPROT ID#>>A0A024QZS3
  UNIPROT ID#>>A0A024QZU7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phospholipid phosphatase 1 interacts with:

• cAMP responsive element binding protein 3
  fumarylacetoacetate hydrolase domain containing 1
  insulin like growth factor 2 mRNA binding protein 2
  phospholipid phosphatase 1
  phospholipid phosphatase 2
  phospholipid phosphatase 3
  serine rich single-pass membrane protein 1
  tripartite motif containing 68

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.