CYC1, cytochrome c1

CYC1, cytochrome c1

• This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6. [provided by RefSeq, Dec 2013]

• Gene Synonyms (cytochrome c1, heme protein, mitochondrial, complex III subunit 4, complex III subunit IV, cytochrome b-c1 complex subunit 4, cytochrome c-1, ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit, MC3DN6, UQCR4,)
• NCBI Gene ID: 1537
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P08574
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cytochrome c1 interacts with:

• AFG3 like matrix AAA peptidase subunit 2
  ankyrin repeat and SOCS box containing 14
  ankyrin repeat domain 34C
  apoptosis inducing factor mitochondria associated 1
  armadillo repeat containing X-linked 3
  ataxin 3
  ATP synthase membrane subunit g
  ATP synthase peripheral stalk subunit d
  ATPase family AAA domain containing 3A
  ATPase family AAA domain containing 3B
  autophagy related 16 like 1
  coronin 1C
  cytochrome c oxidase assembly factor 3
  cytochrome c oxidase subunit 5A
  cytochrome c oxidase subunit 7A2 like
  cytochrome c, somatic
  cytochrome c1
  cytochrome p450 oxidoreductase
  dihydrolipoamide S-acetyltransferase
  dihydroorotate dehydrogenase (quinone)
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  epithelial cell transforming 2
  ER membrane protein complex subunit 2
  ER membrane protein complex subunit 4
  ER membrane protein complex subunit 8
  estrogen receptor 2
  eukaryotic translation elongation factor 2
  EYA transcriptional coactivator and phosphatase 2
  F-box protein 6
  golgi transport 1B
  HAUS augmin-like complex, subunit 1
  heat shock protein 90 beta family member 1
  heat shock protein family B (small) member 1
  heme oxygenase 2
  hexokinase 1
  holocytochrome c synthase
  huntingtin
  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
  hydroxysteroid 17-beta dehydrogenase 12
  ilvB acetolactate synthase like
  inner membrane mitochondrial protein
  keratin 17
  KRAS proto-oncogene, GTPase
  lactamase beta
  lectin, mannose binding 1
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat containing 59
  limb development membrane protein 1 like
  lon peptidase 1, mitochondrial
  MDS1 and EVI1 complex locus
  microsomal glutathione S-transferase 3
  mitochondrial carrier 2
  mitochondrial ribosomal protein L15
  mitochondrial ribosomal protein L37
  mitochondrial ribosomal protein L4
  mitochondrial ribosomal protein L58
  mitochondrially encoded cytochrome b
  mitochondrially encoded cytochrome c oxidase II
  Mov10 RISC complex RNA helicase
  MYC proto-oncogene, bHLH transcription factor
  myosin heavy chain 7B
  myosin light chain 12A
  myosin light chain 6
  myotubularin related protein 12
  NADH:ubiquinone oxidoreductase complex assembly factor 3
  NADH:ubiquinone oxidoreductase core subunit S1
  NADH:ubiquinone oxidoreductase core subunit S2
  NADH:ubiquinone oxidoreductase core subunit S3
  NADH:ubiquinone oxidoreductase core subunit S7
  NADH:ubiquinone oxidoreductase core subunit S8
  NADH:ubiquinone oxidoreductase core subunit V1
  NADH:ubiquinone oxidoreductase core subunit V2
  NADH:ubiquinone oxidoreductase subunit A12
  NADH:ubiquinone oxidoreductase subunit A9
  NADH:ubiquinone oxidoreductase subunit B10
  NADH:ubiquinone oxidoreductase subunit S4
  NADH:ubiquinone oxidoreductase subunit S5
  NDUFA4 mitochondrial complex associated
  neurotrophic receptor tyrosine kinase 1
  NHL repeat containing 2
  nicotinamide nucleotide transhydrogenase
  nipsnap homolog 1
  nipsnap homolog 2
  oxoglutarate dehydrogenase
  paraoxonase 2
  peroxisomal biogenesis factor 19
  PR/SET domain 16
  prohibitin
  prohibitin 2
  prolyl 4-hydroxylase subunit alpha 1
  protein phosphatase 2 scaffold subunit Aalpha
  pyruvate dehydrogenase E1 subunit alpha 1
  pyruvate dehydrogenase E1 subunit beta
  RAB1A, member RAS oncogene family
  RAB1B, member RAS oncogene family
  RAB5 interacting factor
  reticulocalbin 1
  reticulocalbin 2
  ribophorin I
  ring finger protein 4
  RNA pseudouridine synthase D4
  saccharopine dehydrogenase (putative)
  SAMM50 sorting and assembly machinery component
  signal sequence receptor subunit 1
  single stranded DNA binding protein 1
  solute carrier family 25 member 3
  sphingosine-1-phosphate lyase 1
  succinate dehydrogenase complex flavoprotein subunit A
  SURF1 cytochrome c oxidase assembly factor
  testis expressed 101
  transcription factor A, mitochondrial
  transglutaminase 2
  translocase of outer mitochondrial membrane 22
  translocase of outer mitochondrial membrane 40
  translocase of outer mitochondrial membrane 5
  transmembrane and coiled-coil domains 1
  transmembrane phosphatase with tensin homology
  transporter 1, ATP binding cassette subfamily B member
  tropomyosin 3
  Tu translation elongation factor, mitochondrial
  tubulin, beta 4B class IVB
  ubiquinol-cytochrome c reductase binding protein
  ubiquinol-cytochrome c reductase complex III subunit VII
  ubiquinol-cytochrome c reductase core protein 1
  ubiquinol-cytochrome c reductase core protein 2
  ubiquinol-cytochrome c reductase hinge protein
  ubiquinol-cytochrome c reductase, complex III subunit X
  ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
  valosin containing protein
  vir like m6A methyltransferase associated
  voltage dependent anion channel 1
  voltage dependent anion channel 2
  voltage dependent anion channel 3
  zinc finger protein 746
  zinc finger protein 782

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.