NDUFS3, NADH:ubiquinone oxidoreductase core subunit S3

NDUFS3, NADH:ubiquinone oxidoreductase core subunit S3

• This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009]

• Gene Synonyms (CI-30, MC1DN8, NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial, CI-30kD, NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase), NADH dehydrogenase-ubiquinone 30 kDa subunit, NADH-ubiquinone oxidoreductase 30 kDa subunit, complex I 30kDa subunit, complex I-30kD,)
• NCBI Gene ID: 4722
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75489
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NADH:ubiquinone oxidoreductase core subunit S3 interacts with:

• 3-oxoacid CoA-transferase 1
  acyl-CoA dehydrogenase family member 9
  acyl-CoA thioesterase 13
  alkylglycerone phosphate synthase
  ankyrin repeat domain 34C
  apoptosis inducing factor mitochondria associated 1
  armadillo repeat containing 8
  armadillo repeat containing X-linked 3
  ATP synthase peripheral stalk subunit d
  aurora kinase A interacting protein 1
  caseinolytic mitochondrial matrix peptidase chaperone subunit B
  caseinolytic mitochondrial matrix peptidase chaperone subunit X
  CDGSH iron sulfur domain 3
  chromosome 15 open reading frame 48
  coenzyme Q8A
  coenzyme Q9
  coiled-coil-helix-coiled-coil-helix domain containing 10
  coiled-coil-helix-coiled-coil-helix domain containing 2
  coronin 1C
  cullin 3
  cullin 7
  cyclin dependent kinase 20
  cytochrome c oxidase assembly factor 3
  cytochrome c oxidase assembly factor COX14
  cytochrome c oxidase subunit 5A
  cytochrome c oxidase subunit 7A2 like
  cytochrome p450 oxidoreductase
  dehydrogenase/reductase 4
  DNA polymerase delta interacting protein 2
  ECSIT signaling integrator
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  enoyl-CoA delta isomerase 2
  ER membrane protein complex subunit 2
  ER membrane protein complex subunit 4
  ER membrane protein complex subunit 8
  FAD dependent oxidoreductase domain containing 1
  G elongation factor mitochondrial 1
  glutaredoxin 5
  golgi transport 1B
  heat shock protein 90 beta family member 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  HtrA serine peptidase 2
  huntingtin
  hypoxia inducible factor 1 subunit alpha inhibitor
  ilvB acetolactate synthase like
  inner membrane mitochondrial protein
  La ribonucleoprotein 7, transcriptional regulator
  lactamase beta
  late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
  lectin, mannose binding 2
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat containing 59
  limb development membrane protein 1 like
  lon peptidase 1, mitochondrial
  matrix AAA peptidase interacting protein 1
  methenyltetrahydrofolate synthetase
  mitochondrial carrier 2
  mitochondrial contact site and cristae organizing system subunit 10
  mitochondrial ribosomal protein L13
  mitochondrial ribosomal protein L16
  mitochondrial ribosomal protein L22
  mitochondrial ribosomal protein L3
  mitochondrial ribosomal protein L46
  mitochondrial ribosomal protein L53
  mitochondrial ribosomal protein S10
  mitochondrial rRNA methyltransferase 1
  mitogen-activated protein kinase 6
  myosin light chain 12A
  NADH:ubiquinone oxidoreductase complex assembly factor 1
  NADH:ubiquinone oxidoreductase complex assembly factor 3
  NADH:ubiquinone oxidoreductase complex assembly factor 4
  NADH:ubiquinone oxidoreductase complex assembly factor 5
  NADH:ubiquinone oxidoreductase complex assembly factor 8
  NADH:ubiquinone oxidoreductase core subunit S3
  NADH:ubiquinone oxidoreductase core subunit S7
  NADH:ubiquinone oxidoreductase core subunit S8
  NADH:ubiquinone oxidoreductase core subunit V1
  NADH:ubiquinone oxidoreductase core subunit V2
  NADH:ubiquinone oxidoreductase subunit A11
  NADH:ubiquinone oxidoreductase subunit A12
  NADH:ubiquinone oxidoreductase subunit A13
  NADH:ubiquinone oxidoreductase subunit B11
  NADH:ubiquinone oxidoreductase subunit S4
  NADH:ubiquinone oxidoreductase subunit S5
  NADH:ubiquinone oxidoreductase subunit S6
  NADH:ubiquinone oxidoreductase subunit V3
  Nanog homeobox
  nephrocystin 1
  neurotrophic receptor tyrosine kinase 1
  nicotinamide nucleotide transhydrogenase
  nipsnap homolog 1
  non-POU domain containing octamer binding
  NPL4 homolog, ubiquitin recognition factor
  nuclear receptor subfamily 2 group C member 2
  nuclear RNA export factor 1
  OCIA domain containing 1
  oxoglutarate dehydrogenase
  palmitoyl-protein thioesterase 1
  paraoxonase 2
  parkin RBR E3 ubiquitin protein ligase
  Parkinsonism associated deglycase
  peptidase, mitochondrial processing subunit alpha
  peptidase, mitochondrial processing subunit beta
  pitrilysin metallopeptidase 1
  pleckstrin homology domain containing A4
  POU class 5 homeobox 1
  PR/SET domain 16
  prohibitin
  prohibitin 2
  prolyl 4-hydroxylase subunit alpha 1
  propionyl-CoA carboxylase subunit beta
  protein tyrosine phosphatase mitochondrial 1
  protein tyrosine phosphatase non-receptor type 18
  pyridoxal phosphate binding protein
  pyruvate dehydrogenase E1 subunit alpha 1
  pyruvate dehydrogenase E1 subunit beta
  pyruvate dehydrogenase kinase 1
  RAB5 interacting factor
  RAS like family 10 member B
  RecQ like helicase 4
  reticulocalbin 2
  ring finger protein 123
  saccharopine dehydrogenase (putative)
  SAMM50 sorting and assembly machinery component
  sequestosome 1
  serine hydroxymethyltransferase 2
  sideroflexin 1
  sideroflexin 3
  single stranded DNA binding protein 1
  solute carrier family 16 member 1
  solute carrier family 3 member 2
  splicing factor proline and glutamine rich
  sterol O-acyltransferase 1
  stomatin like 2
  succinate dehydrogenase complex flavoprotein subunit A
  SURF1 cytochrome c oxidase assembly factor
  synoviolin 1
  synthesis of cytochrome C oxidase 1
  tectonic family member 3
  TNFAIP3 interacting protein 2
  transcription factor A, mitochondrial
  transforming growth factor beta 1
  translocase of inner mitochondrial membrane 44
  translocase of inner mitochondrial membrane domain containing 1
  translocase of outer mitochondrial membrane 22
  translocase of outer mitochondrial membrane 40
  translocase of outer mitochondrial membrane 5
  transmembrane protein 11
  transmembrane protein 126B
  transmembrane protein 14C
  transmembrane protein 17
  tripartite motif containing 28
  tRNA methyltransferase 61B
  Ts translation elongation factor, mitochondrial
  Tu translation elongation factor, mitochondrial
  ubiquinol-cytochrome c reductase binding protein
  ubiquinol-cytochrome c reductase complex III subunit VII
  ubiquinol-cytochrome c reductase core protein 1
  ubiquinol-cytochrome c reductase core protein 2
  ubiquinol-cytochrome c reductase hinge protein
  ubiquinol-cytochrome c reductase, complex III subunit X
  ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
  ubiquitin C
  ubiquitin protein ligase E3 component n-recognin 2
  valosin containing protein
  vascular cell adhesion molecule 1
  vir like m6A methyltransferase associated
  voltage dependent anion channel 1
  voltage dependent anion channel 2
  voltage dependent anion channel 3
  WW domain containing oxidoreductase
  zinc finger protein 598, E3 ubiquitin ligase
  zinc finger protein 746
  zinc finger protein 782

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.