DAO, D-amino acid oxidase

DAO, D-amino acid oxidase

• This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]

• Gene Synonyms (D-amino-acid oxidase, DAAO, DAMOX, OXDA,)
• NCBI Gene ID: 1610
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P14920
  UNIPROT ID#>>A0A024RBI1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

D-amino acid oxidase interacts with:

• D-amino acid oxidase
  D-amino acid oxidase activator
  E1A binding protein p300
  glutathione S-transferase mu 1
  kelch like family member 42
  NME/NM23 nucleoside diphosphate kinase 2
  peroxisomal biogenesis factor 5
  protein kinase AMP-activated non-catalytic subunit beta 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.