NME2, NME/NM23 nucleoside diphosphate kinase 2

NME2, NME/NM23 nucleoside diphosphate kinase 2

• Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Nov 2010]

• Gene Synonyms (NDKB, NDPK-B, NDPKB, NM23-H2, NM23B, PUF, nucleoside diphosphate kinase B, HEL-S-155an, NDP kinase B, c-myc purine-binding transcription factor PUF, c-myc transcription factor, epididymis secretory sperm binding protein Li 155an, histidine protein kinase NDKB, non-metastatic cells 2, protein (NM23) expressed in, non-metastatic cells 2, protein (NM23B) expressed in, nucleotide diphosphate kinase B,)
• NCBI Gene ID: 4831
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P22392
  UNIPROT ID#>>Q6FHN3
  UNIPROT ID#>>F6XY72
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NME/NM23 nucleoside diphosphate kinase 2 interacts with:

• 3-hydroxyisobutyryl-CoA hydrolase
  A-kinase anchoring protein 13
  aldo-keto reductase family 1 member A1
  BCL2 interacting protein like
  destrin, actin depolymerizing factor
  epiplakin 1
  GIT ArfGAP 2
  H2B clustered histone 4
  HECT and RLD domain containing E3 ubiquitin protein ligase 3
  HECT and RLD domain containing E3 ubiquitin protein ligase 5
  HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
  histone deacetylase 4
  huntingtin interacting protein K
  integrin subunit beta 1 binding protein 1
  leucine rich alpha-2-glycoprotein 1
  MOB family member 4, phocein
  nitric oxide synthase 2
  NME/NM23 nucleoside diphosphate kinase 2
  NME/NM23 nucleoside diphosphate kinase 3
  NME/NM23 nucleoside diphosphate kinase 4
  NME1-NME2 readthrough
  NPC intracellular cholesterol transporter 2
  ornithine aminotransferase
  palmitoyl-protein thioesterase 1
  parkin RBR E3 ubiquitin protein ligase
  PEDS1-UBE2V1 readthrough
  peroxiredoxin 5
  phosphoethanolamine/phosphocholine phosphatase 1
  proteasome 20S subunit alpha 2
  proteasome 20S subunit alpha 7
  protein disulfide isomerase family A member 6
  protein phosphatase 1 regulatory subunit 7
  protein phosphatase 1 regulatory subunit 8
  protein phosphatase 2 catalytic subunit alpha
  protein phosphatase 6 catalytic subunit
  protein phosphatase targeting COQ7
  protein phosphatase, Mg2+/Mn2+ dependent 1K
  protein tyrosine phosphatase non-receptor type 23
  protein tyrosine phosphatase receptor type S
  PTEN induced kinase 1
  RAB5A, member RAS oncogene family
  RAR related orphan receptor A
  RAR related orphan receptor B
  ribosomal protein L38
  ribosomal protein S3
  ribosomal protein S6
  ribosomal protein S6 kinase A2
  ribosomal protein S6 kinase A3
  RNA polymerase II, I and III subunit H
  RuvB like AAA ATPase 2
  solute carrier family 48 member 1
  SPARC related modular calcium binding 1
  stress induced phosphoprotein 1
  superoxide dismutase 1
  supervillin
  telomeric repeat binding factor 1
  thromboxane A2 receptor
  TraB domain containing
  transgelin
  transgelin 2
  transketolase
  ubiquitin conjugating enzyme E2 M
  ubiquitin conjugating enzyme E2 V1
  valosin containing protein
  vimentin
  WD repeat domain 1
  WW domain containing oxidoreductase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.