FARSA, phenylalanyl-tRNA synthetase subunit alpha

FARSA, phenylalanyl-tRNA synthetase subunit alpha

• Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a product which is similar to the catalytic subunit of prokaryotic and Saccharomyces cerevisiae phenylalanyl-tRNA synthetases (PheRS). This gene product has been shown to be expressed in a tumor-selective and cell cycle stage- and differentiation-dependent manner, the first member of the tRNA synthetase gene family shown to exhibit this type of regulated expression [provided by RefSeq, Jul 2008]

• Gene Synonyms (CML33, FARSL, FARSLA, FRSA, PheHA, phenylalanine--tRNA ligase alpha subunit, pheRS, phenylalanine tRNA ligase 1, alpha, cytoplasmic, phenylalanine--tRNA ligase alpha chain, phenylalanine-tRNA synthetase alpha-subunit, phenylalanine-tRNA synthetase-like, alpha subunit, phenylalanyl-tRNA synthetase alpha chain, phenylalanyl-tRNA synthetase alpha subunit, phenylalanyl-tRNA synthetase-like, alpha subunit,)
• NCBI Gene ID: 2193
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y285
  UNIPROT ID#>>Q6IBR2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phenylalanyl-tRNA synthetase subunit alpha interacts with:

• AAR2 splicing factor
  ABI family member 3
  activating signal cointegrator 1 complex subunit 3
  ankyrin repeat and SOCS box containing 4
  autophagy related 16 like 1
  bromodomain containing 7
  chaperonin containing TCP1 subunit 6B
  checkpoint kinase 2
  component of oligomeric golgi complex 4
  cullin 1
  cullin 3
  DNA polymerase delta 1, catalytic subunit
  Ecm29 proteasome adaptor and scaffold
  ECSIT signaling integrator
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  eukaryotic translation initiation factor 2 alpha kinase 2
  factor interacting with PAPOLA and CPSF1
  F-box protein 6
  F-box protein 7
  golgin, RAB6 interacting
  heterogeneous nuclear ribonucleoprotein R
  HEXIM P-TEFb complex subunit 1
  integrin alpha FG-GAP repeat containing 1
  interferon regulatory factor 2 binding protein 1
  limb development membrane protein 1 like
  lysine demethylase 6B
  minichromosome maintenance complex component 2
  mitogen-activated protein kinase 6
  mitotic arrest deficient 2 like 2
  neurofibromin 2
  neurotrophic receptor tyrosine kinase 1
  nuclear receptor subfamily 2 group C member 2
  OFD1 centriole and centriolar satellite protein
  O-linked N-acetylglucosamine (GlcNAc) transferase
  phenylalanyl-tRNA synthetase subunit beta
  phosphoribosyl pyrophosphate synthetase 1
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  poly(A) specific ribonuclease subunit PAN2
  programmed cell death 10
  prohibitin
  proteasome 26S subunit, non-ATPase 14
  proteasome 26S subunit, non-ATPase 4
  proteasome assembly chaperone 2
  pseudouridine synthase 1
  receptor interacting serine/threonine kinase 4
  RecQ like helicase 4
  ribosomal protein L10
  ribosomal protein L35
  ribosomal protein lateral stalk subunit P0
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 32
  snail family transcriptional repressor 1
  solute carrier family 25 member 28
  SRY-box transcription factor 2
  staufen double-stranded RNA binding protein 1
  succinate dehydrogenase complex flavoprotein subunit A
  teratocarcinoma-derived growth factor 1
  threonyl-tRNA synthetase 1
  thymopoietin
  tripartite motif containing 28
  tRNA methyltransferase 5
  ubiquitin C
  ubiquitin specific peptidase 11
  ubiquitin specific peptidase 14
  ubiquitin specific peptidase 32
  unc-93 homolog B1, TLR signaling regulator
  WW domain containing E3 ubiquitin protein ligase 2
  WW domain containing oxidoreductase
  X-ray repair cross complementing 3
  zinc finger protein 598, E3 ubiquitin ligase
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.