AGFG1, ArfGAP with FG repeats 1

AGFG1, ArfGAP with FG repeats 1

• The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

• Gene Synonyms (arf-GAP domain and FG repeat-containing protein 1, HIV-1 Rev-binding protein, Rab, Rev/Rex activation domain-binding protein, arf-GAP domain and FG repeats-containing protein 1, hRIP, Rev interacting protein, nucleoporin-like protein RIP, rev-interacting protein, rev/Rex activation domain-binding protein, HRB, RAB, RIP,)
• NCBI Gene ID: 3267
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z444
  UNIPROT ID#>>P52594
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ArfGAP with FG repeats 1 interacts with:

• actin related protein 2/3 complex subunit 1A
  ArfGAP with FG repeats 1
  ArfGAP with FG repeats 2
  Bet1 golgi vesicular membrane trafficking protein
  cAMP-dependent protein kinase inhibitor alpha
  centrosomal protein 170
  DDB1 and CUL4 associated factor 15
  DNA polymerase epsilon 2, accessory subunit
  DnaJ heat shock protein family (Hsp40) member C5
  drebrin like
  epidermal growth factor receptor pathway substrate 15
  epidermal growth factor receptor pathway substrate 15 like 1
  epidermal growth factor receptor pathway substrate 15-like 1
  exportin 1
  FCH and mu domain containing endocytic adaptor 1
  fibronectin type III and SPRY domain containing 1
  GPN-loop GTPase 1
  HSPA (Hsp70) binding protein 1
  importin 11
  integrin subunit alpha 4
  intersectin 1
  leucine aminopeptidase 3
  LIM domain containing preferred translocation partner in lipoma
  malignant fibrous histiocytoma amplified sequence 1
  membrane palmitoylated protein 1
  mindbomb E3 ubiquitin protein ligase 1
  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
  NGG1 interacting factor 3 like 1
  O-linked N-acetylglucosamine (GlcNAc) transferase
  prolyl 3-hydroxylase 1
  protein phosphatase methylesterase 1
  retinol dehydrogenase 12
  ring finger protein 216
  SH3 domain containing GRB2 like, endophilin B1
  succinate-CoA ligase ADP-forming subunit beta
  surfeit 2
  TP53RK binding protein
  trans-golgi network protein 2
  tripartite motif containing 25
  vascular cell adhesion molecule 1
  vesicle associated membrane protein 7
  ZPR1 zinc finger

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.