IFIT1, interferon induced protein with tetratricopeptide repeats 1

IFIT1, interferon induced protein with tetratricopeptide repeats 1

• This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]

• Gene Synonyms (interferon-induced protein with tetratricopeptide repeats 1, interferon, alpha-inducible protein (MW 56kD), interferon-induced 56 kDa protein, interferon-inducible mRNA 561, C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561,)
• NCBI Gene ID: 3434
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P09914
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interferon induced protein with tetratricopeptide repeats 1 interacts with:

• cyclic GMP-AMP synthase
  dermcidin
  eukaryotic translation initiation factor 3 subunit E
  GrpE like 1, mitochondrial
  insulin like growth factor 2 mRNA binding protein 1
  interferon alpha 10
  interferon alpha 14
  interferon alpha 21
  interferon alpha 5
  interferon alpha 8
  interferon induced protein with tetratricopeptide repeats 1B
  interferon induced protein with tetratricopeptide repeats 3
  interferon induced protein with tetratricopeptide repeats 5
  interleukin enhancer binding factor 2
  ISG15 ubiquitin like modifier
  methylcrotonoyl-CoA carboxylase 1
  methylcrotonoyl-CoA carboxylase 2
  Mov10 RISC complex RNA helicase
  nucleolin
  phosphatase and actin regulator 4
  poly(A) binding protein cytoplasmic 1
  poly(A) binding protein cytoplasmic 4
  propionyl-CoA carboxylase subunit alpha
  propionyl-CoA carboxylase subunit beta
  protein kinase C, zeta
  pyruvate carboxylase
  ribosomal protein lateral stalk subunit P1
  RIO kinase 1
  S100 calcium binding protein A7
  Sin3A associated protein 25
  small nuclear ribonucleoprotein D1 polypeptide
  small nuclear ribonucleoprotein D2 polypeptide
  small nuclear ribonucleoprotein D3 polypeptide
  small nuclear ribonucleoprotein polypeptide A
  small nuclear ribonucleoprotein polypeptide A'
  small nuclear ribonucleoprotein polypeptide B2
  small nuclear ribonucleoprotein polypeptide C
  small nuclear ribonucleoprotein polypeptide E
  small nuclear ribonucleoprotein polypeptide F
  small nuclear ribonucleoprotein polypeptides B and B1
  small nuclear ribonucleoprotein U1 subunit 70
  spire type actin nucleation factor 2
  target of EGR1, exonuclease
  testin LIM domain protein
  transcription factor EB
  Y-box binding protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.