INPP5B, inositol polyphosphate-5-phosphatase B

INPP5B, inositol polyphosphate-5-phosphatase B

• This gene encodes a member of a family of inositol polyphosphate-5-phosphatases. These enzymes function in the regulation of calcium signaling by inactivating inositol phosphates. The encoded protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jul 2014]

• Gene Synonyms (type II inositol 1,4,5-trisphosphate 5-phosphatase, inositol polyphosphate-5-phosphatase, 75kDa, phosphoinositide 5-phosphatase, 5PTase,)
• NCBI Gene ID: 3633
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KMW4
  UNIPROT ID#>>P32019
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

inositol polyphosphate-5-phosphatase B interacts with:

• cell division cycle 26
  centrosomal protein 43
  chromobox 4
  claspin
  DnaJ heat shock protein family (Hsp40) member C11
  dynein cytoplasmic 1 light intermediate chain 1
  Janus kinase 3
  Jun proto-oncogene, AP-1 transcription factor subunit
  kinesin family member 20A
  NUF2 component of NDC80 kinetochore complex
  OCRL inositol polyphosphate-5-phosphatase
  par-6 family cell polarity regulator beta
  PH domain containing endocytic trafficking adaptor 1
  PH domain containing endocytic trafficking adaptor 2
  regulator of microtubule dynamics 3
  ribonuclease H2 subunit A
  SET domain, bifurcated 1
  Shoc2, leucine rich repeat scaffold protein
  SMAD specific E3 ubiquitin protein ligase 1
  tubulin, alpha 3A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.