JUN, Jun proto-oncogene, AP-1 transcription factor subunit

JUN, Jun proto-oncogene, AP-1 transcription factor subunit

• This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]

• Gene Synonyms (AP-1, AP1, c-Jun, cJUN, p39, transcription factor AP-1, Jun activation domain binding protein, activator protein 1, enhancer-binding protein AP1, jun oncogene, proto-oncogene c-Jun, proto-oncogene cJun, v-jun avian sarcoma virus 17 oncogene homolog, v-jun sarcoma virus 17 oncogene homolog,)
• NCBI Gene ID: 3725
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P05412
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Jun proto-oncogene, AP-1 transcription factor subunit interacts with:

• activating transcription factor 7
  adenosylhomocysteinase like 2
  anti-silencing function 1A histone chaperone
  ariadne RBR E3 ubiquitin protein ligase 1
  AT-rich interaction domain 3B
  Bardet-Biedl syndrome 7
  basic leucine zipper ATF-like transcription factor
  basic leucine zipper ATF-like transcription factor 2
  basic leucine zipper ATF-like transcription factor 3
  BEN domain containing 4
  BTG3 associated nuclear protein
  cAMP responsive element binding protein 3
  cAMP responsive element binding protein 5
  caveolae associated protein 1
  cereblon
  clathrin interactor 1
  coiled-coil domain containing 93
  coiled-coil domain containing 97
  COP1 E3 ubiquitin ligase
  COP9 signalosome subunit 2
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  coronin 7
  C-type lectin domain family 3 member A
  cyclin D1 binding protein 1
  DET1 partner of COP1 E3 ubiquitin ligase
  deuterosome assembly protein 1
  DExD-box helicase 21
  DNA ligase 3
  DNA methyltransferase 3 like
  DNA topoisomerase I
  DNA topoisomerase II alpha
  EBF transcription factor 3
  egl-9 family hypoxia inducible factor 3
  elongation factor 1 homolog
  endothelial differentiation related factor 1
  exocyst complex component 1
  F-box and leucine rich repeat protein 12
  F-box and WD repeat domain containing 7
  FOS like 1, AP-1 transcription factor subunit
  golgi associated PDZ and coiled-coil motif containing
  H4 clustered histone 1
  HAUS augmin like complex subunit 6
  heterogeneous nuclear ribonucleoprotein M
  histone cell cycle regulator
  histone deacetylase 3
  histone deacetylase 9
  itchy E3 ubiquitin protein ligase
  Jun dimerization protein 2
  Jun proto-oncogene, AP-1 transcription factor subunit
  JunB proto-oncogene, AP-1 transcription factor subunit
  JunD proto-oncogene, AP-1 transcription factor subunit
  karyopherin subunit alpha 2
  KH-type splicing regulatory protein
  LIM domain 7
  LIM domain only 7
  lysine acetyltransferase 2B
  lysine acetyltransferase 7
  lysine demethylase 2B
  lysine methyltransferase 2C
  MAF bZIP transcription factor
  MAF bZIP transcription factor B
  mannose-6-phosphate receptor, cation dependent
  MAPK activated protein kinase 5
  MDM2 proto-oncogene
  metadherin
  metastasis associated 1
  metastasis associated 1 family member 3
  methyl-CpG binding domain protein 3
  microtubule actin crosslinking factor 1
  microtubule associated protein RP/EB family member 3
  mitogen-activated protein kinase 1
  mitogen-activated protein kinase 10
  mitogen-activated protein kinase 11
  mitogen-activated protein kinase 3
  mitogen-activated protein kinase 8
  mitogen-activated protein kinase 8 interacting protein 1
  mitogen-activated protein kinase 9
  mitogen-activated protein kinase kinase 4
  mitogen-activated protein kinase kinase 7
  mitogen-activated protein kinase kinase kinase 1
  MLLT6, PHD finger containing
  MOK protein kinase
  mucin 1, cell surface associated
  MYB binding protein 1a
  MYC associated factor X
  MYC associated zinc finger protein
  MYC proto-oncogene, bHLH transcription factor
  myocyte enhancer factor 2A
  myocyte enhancer factor 2D
  myogenic differentiation 1
  N-acetyltransferase 14 (putative)
  nascent polypeptide associated complex subunit alpha
  NBR1 autophagy cargo receptor
  NCK interacting protein with SH3 domain
  NEDD4 E3 ubiquitin protein ligase
  negative elongation factor complex member B
  neurotrophic receptor tyrosine kinase 3
  NFKB repressing factor
  nuclear factor I X
  nuclear factor of activated T cells 1
  nuclear factor of activated T cells 2
  nuclear factor of activated T cells 4
  nuclear factor of activated T cells 5
  nuclear factor, erythroid 2 like 1
  nuclear factor, erythroid 2 like 2
  nuclear receptor coactivator 1
  nuclear receptor coactivator 2
  nuclear receptor coactivator 3
  nuclear receptor coactivator 6
  nuclear receptor corepressor 1
  nuclear receptor corepressor 2
  nuclear receptor interacting protein 1
  nuclear transcription factor Y subunit alpha
  Opa interacting protein 5
  PDS5 cohesin associated factor A
  peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  peroxisome proliferator activated receptor gamma
  PHD finger protein 21A
  phosphofurin acidic cluster sorting protein 1
  pleckstrin homology domain containing O1
  pleckstrin homology like domain family B member 3
  PML nuclear body scaffold
  POU class 1 homeobox 1
  proline rich coiled-coil 2A
  protein inhibitor of activated STAT 1
  protein inhibitor of activated STAT 2
  protein kinase D1
  protein kinase, DNA-activated, catalytic subunit
  protein phosphatase 2 regulatory subunit Bdelta
  protein phosphatase 3 catalytic subunit alpha
  protein phosphatase 3 catalytic subunit beta
  protein phosphatase 4 catalytic subunit
  ralA binding protein 1
  Ran GTPase activating protein 1
  RB transcriptional corepressor 1
  receptor for activated C kinase 1
  regulation of nuclear pre-mRNA domain containing 1A
  RELA proto-oncogene, NF-kB subunit
  Rho GTPase activating protein 22
  ribosomal protein L18a
  ribosomal protein S6 kinase A2
  ring finger protein 187
  RNA binding motif protein 39
  SATB homeobox 1
  SATB homeobox 2
  signal transducer and activator of transcription 1
  signal transducer and activator of transcription 3
  signal transducer and activator of transcription 4
  signal transducer and activator of transcription 6
  sirtuin 1
  SIX homeobox 4
  SKI proto-oncogene
  SMAD family member 2
  SMAD family member 3
  SMAD family member 4
  small nuclear RNA activating complex polypeptide 5
  small ubiquitin like modifier 1
  small ubiquitin like modifier 2
  small ubiquitin like modifier 3
  small ubiquitin like modifier 4
  SNF related kinase
  Sp1 transcription factor
  Spi-1 proto-oncogene
  Spi-B transcription factor
  SRY-box transcription factor 10
  SRY-box transcription factor 2
  SRY-box transcription factor 8
  striatin 4
  SUMO/sentrin specific peptidase 2
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  TATA-box binding protein
  TATA-box binding protein associated factor 1
  TATA-box binding protein associated factor 4
  TCL1 family AKT coactivator A
  TGFB induced factor homeobox 1
  thymine DNA glycosylase
  thyroid hormone receptor interactor 4
  TNF receptor associated factor 2
  TNFAIP3 interacting protein 2
  transcription factor 20
  transcription factor 4
  transcription factor AP-2 alpha
  transmembrane p24 trafficking protein 1
  tripartite motif containing 33
  tropomyosin 1
  tropomyosin 2
  tropomyosin 3
  tumor protein p73
  tumor susceptibility 101
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  ubinuclein 1
  ubiquitin B
  ubiquitin C
  ubiquitin conjugating enzyme E2 I
  ubiquitin specific peptidase 6
  UBX domain protein 7
  valyl-tRNA synthetase 1
  vav guanine nucleotide exchange factor 1
  vir like m6A methyltransferase associated
  vitamin D receptor
  VRK serine/threonine kinase 1
  Yes1 associated transcriptional regulator
  zinc finger and BTB domain containing 7C

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.