MEF2D, myocyte enhancer factor 2D

MEF2D, myocyte enhancer factor 2D

• This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]

• Gene Synonyms (myocyte-specific enhancer factor 2D, MADS box transcription enhancer factor 2, polypeptide D,)
• NCBI Gene ID: 4209
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14814
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

myocyte enhancer factor 2D interacts with:

• ASH2 like, histone lysine methyltransferase complex subunit
  calcineurin binding protein 1
  coactivator associated arginine methyltransferase 1
  COP9 signalosome subunit 5
  cyclin-dependent kinase 4
  DNA methyltransferase 3 like
  exportin 1
  F-box protein 7
  histone cell cycle regulator
  histone deacetylase 3
  histone deacetylase 4
  histone deacetylase 5
  lysine acetyltransferase 2B
  lysine methyltransferase 2D
  menin 1
  mitogen-activated protein kinase 7
  Mov10 RISC complex RNA helicase
  myocyte enhancer factor 2B
  myocyte enhancer factor 2D
  nuclear factor of activated T cells 2
  nuclear RNA export factor 1
  protein arginine methyltransferase 5
  protein kinase cAMP-activated catalytic subunit alpha
  protein phosphatase 1 catalytic subunit alpha
  RB binding protein 5, histone lysine methyltransferase complex subunit
  serine hydroxymethyltransferase 2
  Sp1 transcription factor
  S-phase kinase associated protein 2
  SUMO specific peptidase 3
  synuclein alpha
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.