MOS, MOS proto-oncogene, serine/threonine kinase

MOS, MOS proto-oncogene, serine/threonine kinase

• MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009]

• Gene Synonyms (MSV, proto-oncogene serine/threonine-protein kinase mos, c-mos, oncogene MOS, Moloney murine sarcoma virus, oocyte maturation factor mos, proto-oncogene c-Mos, v-mos Moloney murine sarcoma viral oncogene homolog,)
• NCBI Gene ID: 4342
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P00540
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MOS proto-oncogene, serine/threonine kinase interacts with:

• ankyrin repeat and SOCS box containing 6
  ATR interacting protein
  baculoviral IAP repeat containing 6
  BICD cargo adaptor 2
  BLOC-1 related complex subunit 6
  calcium binding and coiled-coil domain 2
  chibby family member 2
  clustered mitochondria homolog
  coiled-coil domain containing 102B
  coiled-coil domain containing 136
  coiled-coil domain containing 33
  cyclin D1 binding protein 1
  DAZ interacting zinc finger protein 1
  DPY30 domain containing 1
  golgin A6 family like 9
  golgin A6 family member A
  GRB2 related adaptor protein 2
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  homeobox and leucine zipper encoding
  homer scaffold protein 3
  IKAROS family zinc finger 1
  keratin 27
  keratin 40
  keratin associated protein 1-3
  kinesin associated protein 3
  leucine zipper tumor suppressor 2
  microtubule associated scaffold protein 2
  midline 2
  MINDY lysine 48 deubiquitinase 3
  mirror-image polydactyly 1
  mitogen-activated protein kinase kinase 2
  MYC proto-oncogene, bHLH transcription factor
  myogenic differentiation 1
  myotubularin related protein 9
  NBPF member 19
  notch 2 N-terminal like A
  potassium channel tetramerization domain containing 6
  proline-serine-threonine phosphatase interacting protein 1
  protein interacting with PRKCA 1
  protein phosphatase 2 regulatory subunit B'alpha
  protein phosphatase 2 regulatory subunit B'epsilon
  ras homolog family member U
  SEC24 homolog C, COPII coat complex component
  serine/threonine kinase 25
  serine/threonine kinase 26
  SSX family member 2 interacting protein
  TNF receptor associated factor 1
  TNF receptor associated factor 2
  tripartite motif containing 27
  tumor protein p53 binding protein 2
  USH1 protein network component harmonin binding protein 1
  zinc finger and BTB domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.