MVD, mevalonate diphosphate decarboxylase

MVD, mevalonate diphosphate decarboxylase

• The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. [provided by RefSeq, Jul 2008]

• Gene Synonyms (FP17780, MDDase, MPD, POROK7, diphosphomevalonate decarboxylase, mevalonate (diphospho) decarboxylase, mevalonate pyrophosphate decarboxylase,)
• NCBI Gene ID: 4597
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P53602
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mevalonate diphosphate decarboxylase interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  ATPase H+ transporting V0 subunit d1
  B-TFIID TATA-box binding protein associated factor 1
  carnosine dipeptidase 2
  cathepsin A
  FTO alpha-ketoglutarate dependent dioxygenase
  G protein subunit beta 5
  GINS complex subunit 2
  guanine deaminase
  kynureninase
  ligand dependent nuclear receptor interacting factor 1
  mediator complex subunit 22
  mevalonate diphosphate decarboxylase
  N-acetylneuraminate synthase
  nicotinamide phosphoribosyltransferase
  N-myc downstream regulated 1
  peptidase D
  pleckstrin homology domain containing A4
  ribosomal protein S6 kinase A1
  SET domain containing 1B, histone lysine methyltransferase
  structural maintenance of chromosomes 3
  tripartite motif containing 25
  WD repeat domain 1
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.