NFYB, nuclear transcription factor Y subunit beta

NFYB, nuclear transcription factor Y subunit beta

• The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CBF-A, CBF-B, HAP3, NF-YB, nuclear transcription factor Y subunit beta, CAAT box DNA-binding protein subunit B, CCAAT-binding transcription factor subunit A, Transcription factor NF-Y, B subunit, nuclear transcription factor Y subunit B, nuclear transcription factor Y, beta,)
• NCBI Gene ID: 4801
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RBG7
  UNIPROT ID#>>P25208
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear transcription factor Y subunit beta interacts with:

• angiotensin II receptor associated protein
  CCAAT enhancer binding protein zeta
  contactin 2
  coronin 1B
  DNA polymerase epsilon 4, accessory subunit
  DR1 associated protein 1
  L antigen family member 3
  lysine acetyltransferase 2B
  nuclear transcription factor Y subunit gamma
  nuclear transcription factor-Y alpha
  nuclear transcription factor-Y gamma
  O-sialoglycoprotein endopeptidase
  POU class 3 homeobox 2
  SET and MYND domain containing 3
  Sp1 transcription factor
  TATA-box binding protein
  TATA-box binding protein associated factor 11
  TATA-box binding protein associated factor 12
  TATA-box binding protein associated factor 6
  tumor protein p53
  tumor protein p73
  Y-box binding protein 1
  Y-box binding protein 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.