CDK16, cyclin dependent kinase 16

CDK16, cyclin dependent kinase 16

• The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]

• Gene Synonyms (PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1, cyclin-dependent kinase 16, PCTAIRE-motif protein kinase 1, cell division protein kinase 16, serine/threonine-protein kinase PCTAIRE-1, testis secretory sperm-binding protein Li 224n,)
• NCBI Gene ID: 5127
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BRL4
  UNIPROT ID#>>A0A024R183
  UNIPROT ID#>>Q00536
  UNIPROT ID#>>A0A140VK97
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cyclin dependent kinase 16 interacts with:

• amyloid beta precursor protein binding protein 2
  ankyrin repeat domain 34A
  ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
  ATR interacting protein
  BAG cochaperone 6
  calmodulin regulated spectrin associated protein family member 2
  chibby family member 1, beta catenin antagonist
  ciliogenesis associated kinase 1
  cingulin
  cyclin dependent kinase 16
  cyclin dependent kinase 17
  cyclin dependent kinase 18
  cyclin dependent kinase 5 regulatory subunit 1
  cyclin Y
  cyclin Y like 1
  cyclin-dependent kinase 1
  DENN domain containing 1A
  DENN domain containing 4C
  DEP domain containing 1B
  doublecortin like kinase 1
  enhancer of mRNA decapping 3
  eukaryotic translation initiation factor 4E family member 2
  exportin 1
  family with sequence similarity 110 member A
  family with sequence similarity 110 member B
  family with sequence similarity 53 member C
  GRB10 interacting GYF protein 1
  GRB2 associated binding protein 2
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 4
  interferon stimulated exonuclease gene 20 like 2
  kinase suppressor of ras 1
  kinesin family member 13B
  kinesin family member 1C
  La ribonucleoprotein 7, transcriptional regulator
  leucine rich repeat and fibronectin type III domain containing 1
  LIM domain and actin binding 1
  MAPK associated protein 1
  maternal embryonic leucine zipper kinase
  membrane associated guanylate kinase, WW and PDZ domain containing 1
  microtubule associated serine/threonine kinase 3
  minichromosome maintenance complex binding protein
  mitogen-activated protein kinase kinase kinase 21
  myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1
  NAD kinase
  nucleoporin 54
  pleckstrin homology domain containing A4
  pleckstrin homology domain containing A5
  pleckstrin homology domain containing A7
  pleckstrin homology like domain family B member 2
  potassium channel tetramerization domain containing 3
  praja ring finger ubiquitin ligase 1
  protein kinase cAMP-activated catalytic subunit alpha
  protein phosphatase 2 catalytic subunit beta
  protein phosphatase 2 regulatory subunit Balpha
  protein phosphatase 2 regulatory subunit Bdelta
  protein phosphatase, Mg2+/Mn2+ dependent 1H
  pyruvate kinase M1/2
  RAB3A interacting protein
  RAS protein activator like 2
  rhotekin
  S100 calcium binding protein A10
  Sec23 homolog A, COPII coat complex component
  serine and arginine rich splicing factor 12
  SH3 and PX domains 2A
  SH3 domain binding protein 4
  SH3 domain containing kinase binding protein 1
  signal induced proliferation associated 1 like 1
  signal regulatory protein alpha
  SLIT-ROBO Rho GTPase activating protein 2
  sodium channel and clathrin linker 1
  sorting nexin 27
  synapse defective Rho GTPase homolog 1
  testis associated actin remodelling kinase 2
  TIAM Rac1 associated GEF 1
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  ubiquitin specific peptidase 21
  zinc finger and BTB domain containing 14
  zinc finger and BTB domain containing 21
  zinc finger protein 638

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.