PPP5C, protein phosphatase 5 catalytic subunit

PPP5C, protein phosphatase 5 catalytic subunit

• This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]

• Gene Synonyms (serine/threonine-protein phosphatase 5, PP-T, protein phosphatase T, PP5, PPP5, PPT,)
• NCBI Gene ID: 5536
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P53041
  UNIPROT ID#>>A0A024R0Q7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 5 catalytic subunit interacts with:

• 3-hydroxyacyl-CoA dehydratase 3
  3'-phosphoadenosine 5'-phosphosulfate synthase 1
  abhydrolase domain containing 14A
  activator of HSP90 ATPase activity 1
  argonaute RISC catalytic component 3
  argonaute RISC component 1
  ATP binding cassette subfamily F member 2
  BAG cochaperone 2
  basic leucine zipper and W2 domains 2
  CDC42 binding protein kinase beta
  cell division cycle 16
  cell division cycle 37 like 1
  cell division cycle 37, HSP90 cochaperone
  centlein
  chaperonin containing TCP1 subunit 4
  copine 1
  copine 2
  copine 4
  cyclin dependent kinase 20
  cysteine and histidine rich domain containing 1
  cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
  decapping enzyme, scavenger
  DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
  DISC1 scaffold protein
  egl-9 family hypoxia inducible factor 3
  elongator acetyltransferase complex subunit 3
  elongator complex protein 1
  EPM2A glucan phosphatase, laforin
  exportin 1
  far upstream element binding protein 1
  folliculin
  G protein subunit alpha 13
  GINS complex subunit 3
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  insulin receptor substrate 4
  integrin beta 1 binding protein 2
  leucine rich repeat containing 1
  mitogen-activated protein kinase kinase kinase 6
  mitogen-activated protein kinase kinase kinase 7
  multiple inositol-polyphosphate phosphatase 1
  myotubularin related protein 7
  nicotinate phosphoribosyltransferase
  nuclear distribution C, dynein complex regulator
  nuclear RNA export factor 1
  nucleolar protein 10
  nucleolar protein 9
  paraspeckle component 1
  PH domain and leucine rich repeat protein phosphatase 1
  phosphatase and tensin homolog
  phospholipase D family member 3
  pleckstrin homology domain containing A4
  pre-mRNA processing factor 8
  presenilin 2
  prostaglandin E synthase 3
  protein phosphatase 5 catalytic subunit
  RAB41, member RAS oncogene family
  Rap1 GTPase-GDP dissociation stimulator 1
  RB binding protein 5, histone lysine methyltransferase complex subunit
  RB binding protein 6, ubiquitin ligase
  receptor for activated C kinase 1
  receptor interacting serine/threonine kinase 4
  RecQ like helicase 4
  ribosomal protein S6 kinase B1
  serine hydroxymethyltransferase 2
  SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
  small nuclear ribonucleoprotein U5 subunit 200
  stress induced phosphoprotein 1
  TatD DNase domain containing 1
  TNFAIP3 interacting protein 2
  transmembrane phosphatase with tensin homology
  tripartite motif containing 25
  Tu translation elongation factor, mitochondrial
  tumor protein p53 binding protein 1
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  ubiquitin specific peptidase 45
  ubiquitin specific peptidase 49
  vimentin
  vinculin
  von Hippel-Lindau tumor suppressor
  WW domain containing oxidoreductase
  YY1 associated factor 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.