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PSMA1, proteasome 20S subunit alpha 1

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PSMA1, proteasome 20S subunit alpha 1

  • The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]

  • Gene Synonyms (proteasome subunit alpha type-1, 30 kDa prosomal protein, PROS-30, epididymis secretory protein Li 275, macropain subunit C2, macropain subunit nu, multicatalytic endopeptidase complex subunit C2, proteasome (prosome, macropain) subunit, alpha type, 1, proteasome component C2, proteasome nu chain, proteasome subunit alpha 1, proteasome subunit alpha 6, proteasome subunit nu, proteasome subunit, alpha-type, 1, protein P30-33K, testicular tissue protein Li 150, HC2, HEL-S-275, NU, PROS30,)
  • NCBI Gene ID: 5682
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>P25786
    UNIPROT ID#>>B4E0X6
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

proteasome 20S subunit alpha 1 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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