CSTF3, cleavage stimulation factor subunit 3

CSTF3, cleavage stimulation factor subunit 3

• The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Gene Synonyms (cleavage stimulation factor subunit 3, CF-1 77 kDa subunit, CSTF 77 kDa subunit, cleavage stimulation factor 77 kDa subunit, cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kD, cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa, CSTF-77,)
• NCBI Gene ID: 1479
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q12996
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cleavage stimulation factor subunit 3 interacts with:

• autophagy related 16 like 1
  cell division cycle 73
  centromere protein K
  cleavage and polyadenylation specific factor 1
  cleavage and polyadenylation specific factor 3
  cleavage stimulation factor subunit 2 tau variant
  cleavage stimulation factor subunit 3
  complement C1q like 4
  COP9 signalosome subunit 4
  cullin 3
  cullin 7
  cyclin L2
  cytochrome P450 family 1 subfamily A member 1
  decapping enzyme, scavenger
  dihydrolipoamide dehydrogenase
  E2F transcription factor 4
  epidermal growth factor receptor
  estrogen receptor 2
  exportin 1
  factor interacting with PAPOLA and CPSF1
  Fas associated factor 1
  G protein nucleolar 3 like
  general transcription factor IIE subunit 2
  glyceraldehyde-3-phosphate dehydrogenase
  H3 clustered histone 1
  heat shock protein family A (Hsp70) member 8
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  heterogeneous nuclear ribonucleoprotein A1
  heterogeneous nuclear ribonucleoprotein L
  limb development membrane protein 1 like
  methionyl aminopeptidase 2
  mono-ADP ribosylhydrolase 1
  myosin, heavy polypeptide 9, non-muscle
  NADH:ubiquinone oxidoreductase subunit B1
  neurotrophic receptor tyrosine kinase 1
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 1
  poly(A) binding protein cytoplasmic 3
  poly(A) polymerase alpha
  poly(A) polymerase beta
  RB binding protein 6, ubiquitin ligase
  RecQ like helicase 4
  RNA binding protein with serine rich domain 1
  RNA polymerase II subunit A
  sequestosome 1
  small nuclear ribonucleoprotein U1 subunit 70
  SNW domain containing 1
  SSU72 homolog, RNA polymerase II CTD phosphatase
  staufen double-stranded RNA binding protein 1
  stem-loop binding protein
  symplekin
  TNFAIP3 interacting protein 2
  tripartite motif containing 25
  tumor protein p53 binding protein 1
  unk zinc finger
  von Hippel-Lindau tumor suppressor
  WW domain containing oxidoreductase
  zinc finger and BTB domain containing 10

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.