FCGR2A, Fc fragment of IgG receptor IIa

FCGR2A, Fc fragment of IgG receptor IIa

• This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

• Gene Synonyms (CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, IGFR2, low affinity immunoglobulin gamma Fc region receptor II-a, Fc fragment of IgG, low affinity IIa, receptor (CD32), Fc gamma receptor RIIa3, Immunoglobulin G Fc receptor II, fc-gamma-RIIa, fcRII-a, igG Fc receptor II-a,)
• NCBI Gene ID: 2212
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P12318
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Fc fragment of IgG receptor IIa interacts with:

• 1-acylglycerol-3-phosphate O-acyltransferase 4
  actin related protein 2/3 complex inhibitor
  ADAM metallopeptidase domain 33
  ADP-ribosylserine hydrolase
  ArfGAP with FG repeats 1
  CDP-diacylglycerol--inositol 3-phosphatidyltransferase
  chondroitin sulfate N-acetylgalactosaminyltransferase 2
  CKLF like MARVEL transmembrane domain containing 5
  C-X-C motif chemokine ligand 9
  early endosome antigen 1
  Fc fragment of IgG receptor IIb
  Fc fragment of IgG receptor IIc (gene/pseudogene)
  fumarylacetoacetate hydrolase domain containing 2A
  FXYD domain containing ion transport regulator 3
  FYN proto-oncogene, Src family tyrosine kinase
  galectin 3
  glycoprotein VI platelet
  growth factor receptor bound protein 2
  GTPase, IMAP family member 1
  HCK proto-oncogene, Src family tyrosine kinase
  integrin subunit alpha 4
  linker for activation of T cells
  LYN proto-oncogene, Src family tyrosine kinase
  major intrinsic protein of lens fiber
  neuronal vesicle trafficking associated 1
  nuclear transcription factor Y subunit gamma
  phosphoinositide-3-kinase regulatory subunit 1
  phosphoribosyl transferase domain containing 1
  plastin 1
  protein phosphatase 3 regulatory subunit B, alpha
  protein tyrosine phosphatase non-receptor type 11
  pyridoxal phosphate binding protein
  SHC adaptor protein 1
  spleen associated tyrosine kinase
  stress associated endoplasmic reticulum protein family member 2
  testin LIM domain protein
  tripartite motif containing 21
  ubiquilin 1
  ubiquitin conjugating enzyme E2 D2
  uroplakin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.