FGL1, fibrinogen like 1

FGL1, fibrinogen like 1

• Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (HFREP1, HP-041, HPS, LFIRE-1, LFIRE1, fibrinogen-like protein 1, hepassocin, hepatocellular carcinoma-related sequence, hepatocyte-derived fibrinogen-related protein 1, liver fibrinogen-related protein 1,)
• NCBI Gene ID: 2267
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q08830
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

fibrinogen like 1 interacts with:

• 2-oxoglutarate and iron dependent oxygenase domain containing 1
  afadin, adherens junction formation factor
  alanyl-tRNA synthetase 2, mitochondrial
  aldehyde dehydrogenase 5 family member A1
  AMMECR1 like
  ankyrin repeat and LEM domain containing 2
  ataxin 2
  BCL2 like 11
  BLOC-1 related complex subunit 5
  BLOC-1 related complex subunit 6
  chromosome 1 open reading frame 198
  collagen type XIV alpha 1 chain
  CWF19 like cell cycle control factor 2
  cytidine monophosphate N-acetylneuraminic acid synthetase
  DDB1 and CUL4 associated factor 16
  dihydropyrimidinase like 5
  dynamin 1 like
  epiplakin 1
  ETHE1 persulfide dioxygenase
  family with sequence similarity 172 member A
  F-box protein 38
  fibrinogen like 1
  general transcription factor IIH subunit 1
  general transcription factor IIH subunit 2
  general transcription factor IIH subunit 3
  glucagon like peptide 1 receptor
  golgi membrane protein 1
  large 60S subunit nuclear export GTPase 1
  leucine carboxyl methyltransferase 2
  metabolism of cobalamin associated D
  microtubule associated protein 1S
  microtubule associated protein RP/EB family member 2
  NAD(P)HX dehydratase
  NADH:ubiquinone oxidoreductase subunit S6
  N-alpha-acetyltransferase 35, NatC auxiliary subunit
  nipsnap homolog 3A
  NOP2/Sun RNA methyltransferase 2
  nucleobindin 1
  peptidylprolyl isomerase like 2
  peroxidasin
  plasminogen activator, tissue type
  pleckstrin homology domain containing A7
  protein phosphatase 1 regulatory inhibitor subunit 1A
  protein tyrosine phosphatase non-receptor type 23
  receptor interacting serine/threonine kinase 1
  Rho/Rac guanine nucleotide exchange factor 2
  ribonucleoprotein, PTB binding 1
  RNA binding motif protein 6
  SAFB like transcription modulator
  sortilin related receptor 1
  spermatogenesis associated serine rich 2 like
  TBC1 domain family member 10A
  terminal uridylyl transferase 1, U6 snRNA-specific
  thyroid hormone receptor interactor 6
  TLE family member 1, transcriptional corepressor
  TLE family member 3, transcriptional corepressor
  transcription factor 25
  TSR3 ribosome maturation factor
  tubulin delta 1
  tubulin epsilon 1
  tubulin epsilon and delta complex 2
  tuftelin interacting protein 11
  ubiquitin like modifier activating enzyme 5
  ubiquitin protein ligase E3 component n-recognin 1
  vitamin K epoxide reductase complex subunit 1
  zinc binding alcohol dehydrogenase domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.