KCNJ2, potassium inwardly rectifying channel subfamily J member 2

KCNJ2, potassium inwardly rectifying channel subfamily J member 2

• Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ATFB9, HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7, SQT3, inward rectifier potassium channel 2, IRK-1, cardiac inward rectifier potassium channel, hIRK1, inward rectifier K+ channel KIR2.1, potassium channel, inwardly rectifying subfamily J, member 2, potassium voltage-gated channel subfamily J member 2,)
• NCBI Gene ID: 3759
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P63252
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium inwardly rectifying channel subfamily J member 2 interacts with:

• ADP ribosylation factor like GTPase 13B
  A-kinase anchoring protein 5
  arginyl aminopeptidase
  calcium/calmodulin dependent serine protein kinase
  dermcidin
  epiplakin 1
  eukaryotic translation initiation factor 3 subunit M
  filaggrin family member 2
  mannosidase alpha class 1B member 1
  non-POU domain containing octamer binding
  non-SMC condensin I complex subunit D2
  PATJ crumbs cell polarity complex component
  potassium inwardly rectifying channel subfamily J member 11
  potassium inwardly rectifying channel subfamily J member 15
  potassium inwardly rectifying channel subfamily J member 16
  potassium inwardly rectifying channel subfamily J member 18
  potassium inwardly rectifying channel subfamily J member 2
  potassium inwardly rectifying channel subfamily J member 4
  potassium inwardly rectifying channel subfamily J member 8
  Rho associated coiled-coil containing protein kinase 2
  SEC22 homolog A, vesicle trafficking protein
  serine/threonine kinase 38
  syndecan 3
  syndecan binding protein
  trafficking kinesin protein 2
  transportin 1
  ubiquitin specific peptidase 15
  ubiquitination factor E4A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.